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Aleth Gaillard
Researcher at Massachusetts Institute of Technology
Publications - 5
Citations - 3277
Aleth Gaillard is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Mutant & Cell. The author has an hindex of 5, co-authored 5 publications receiving 2319 citations. Previous affiliations of Aleth Gaillard include University of Florida.
Papers
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Journal ArticleDOI
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
Itay Tirosh,Benjamin Izar,Benjamin Izar,Sanjay M. Prakadan,Marc H. Wadsworth,Daniel J. Treacy,John J. Trombetta,Asaf Rotem,Asaf Rotem,Christopher Rodman,Christine G. Lian,George F. Murphy,Mohammad Fallahi-Sichani,Ken Dutton-Regester,Ken Dutton-Regester,Ken Dutton-Regester,Jia-Ren Lin,Ofir Cohen,Parin Shah,Diana Lu,Alex S. Genshaft,Travis K. Hughes,Carly G. K. Ziegler,Samuel W. Kazer,Aleth Gaillard,Kellie E. Kolb,Alexandra-Chloé Villani,Cory M. Johannessen,Aleksandr Andreev,Eliezer M. Van Allen,Eliezer M. Van Allen,Monica M. Bertagnolli,Monica M. Bertagnolli,Peter K. Sorger,Ryan J. Sullivan,Keith T. Flaherty,Dennie T. Frederick,Judit Jané-Valbuena,Charles H. Yoon,Charles H. Yoon,Orit Rozenblatt-Rosen,Alex K. Shalek,Aviv Regev,Aviv Regev,Aviv Regev,Levi A. Garraway +45 more
TL;DR: The cellular ecosystem of tumors is begin to unravel and how single-cell genomics offers insights with implications for both targeted and immune therapies is unraveled.
Journal ArticleDOI
Contributions of the S100A9 C-terminal tail to high-affinity Mn(II) chelation by the host-defense protein human calprotectin.
TL;DR: Damo et al. as discussed by the authors showed that the C-terminal tail is essential for high-affinity Mn(II)-coordination by calprotectin in solution, which is in agreement with a Mn-II-calprotectin crystal structure reported recently.
Journal ArticleDOI
Calcium ions tune the zinc-sequestering properties and antimicrobial activity of human S100A12
TL;DR: Human S100A12 exhibits Ca(II)-dependent Zn(ii)-binding properties and antifungal activity and it is unclear whether this property is related to Zn-binding properties or not.
Journal ArticleDOI
Modeling biological copper clusters: synthesis of a tricopper complex, and its chloride- and sulfide-bridged congeners.
TL;DR: The synthesis and characterization of a family of tricopper clusters housed within a tris(β-diketimine) cyclophane ligand (H3L) that bear structural similarities to biological copper clusters are reported.
Patent
Crispr mediated recording of cellular events
Alex K. Shalek,Aleth Gaillard +1 more
TL;DR: In this paper, a method of determining a cellular event of interest in a cell comprising of a CRISPR-Cas system is presented. Butt et al. proposed to detect the modification of the selected DNA sequence based on detection of the modified DNA sequence.