A
Alex Jiao
Researcher at University of Washington
Publications - 16
Citations - 1057
Alex Jiao is an academic researcher from University of Washington. The author has contributed to research in topics: Nanotopography & Tissue engineering. The author has an hindex of 12, co-authored 15 publications receiving 890 citations. Previous affiliations of Alex Jiao include University of Michigan.
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Journal ArticleDOI
Nanotopography-guided tissue engineering and regenerative medicine ☆
Hong Nam Kim,Alex Jiao,Nathaniel S. Hwang,Min Sung Kim,Do Hyun Kang,Deok Ho Kim,Kahp-Yang Suh +6 more
TL;DR: An extensive analysis of recent efforts to mimic functional nanostructures in vitro for improved tissue engineering and regeneration of injured and damaged tissues shows that the nanotopography itself can activate tissue-specific function in vitro as well as promote tissue regeneration in vivo upon transplantation.
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Patterning Methods for Polymers in Cell and Tissue Engineering
TL;DR: This review provides a brief overview of patterning methods of various polymers with a particular focus on biocompatibility and processability and discusses how micro- and nanofabricated polymeric substrates of tunable elastic modulus can be used to engineer cell and tissue structure and function.
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Nanotopography-Induced Structural Anisotropy and Sarcomere Development in Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells
Daniel Carson,Marketa Hnilova,Xiulan Yang,Cameron L. Nemeth,Jonathan H. Tsui,Alec S.T. Smith,Alex Jiao,Michael Regnier,Charles E. Murry,Candan Tamerler,Deok Ho Kim +10 more
TL;DR: A nanogrid culture array comprised of nanogrooved topographies, with groove widths ranging from 350 to 2000 nm, is presented to study the effect of different nanoscale structures on the structural development of hiPSC-CMs in vitro.
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Fabrication of poly(ethylene glycol): gelatin methacrylate composite nanostructures with tunable stiffness and degradation for vascular tissue engineering
TL;DR: In this paper, the elasticity and degradation rate of the composite PEG-GelMA nanostructures were tuned by varying the ratios of PEGDMA and GelMA.
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Thermoresponsive nanofabricated substratum for the engineering of three-dimensional tissues with layer-by-layer architectural control
Alex Jiao,Nicole E. Trosper,Hee Seok Yang,Hee Seok Yang,Jinsung Kim,Jonathan H. Tsui,Samuel D. Frankel,Charles E. Murry,Deok Ho Kim +8 more
TL;DR: A simple and versatile platform combining a thermoresponsive nanofabricated substratum (TNFS) incorporating nanotopographical cues and the gel casting method for the fabrication of scaffold-free 3D tissues with hierarchical control of overall tissue structure is developed.