A
Alex Kirkham
Researcher at University College Hospital
Publications - 98
Citations - 5028
Alex Kirkham is an academic researcher from University College Hospital. The author has contributed to research in topics: Prostate cancer & Magnetic resonance imaging. The author has an hindex of 22, co-authored 88 publications receiving 3961 citations. Previous affiliations of Alex Kirkham include University College London & The Turing Institute.
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Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study
Hashim U. Ahmed,Hashim U. Ahmed,Ahmed El-Shater Bosaily,Ahmed El-Shater Bosaily,Louise Brown,Rhian Gabe,Richard Kaplan,Mahesh K.B. Parmar,Yolanda Collaco-Moraes,Katie Ward,Richard Hindley,Alex Freeman,Alex Kirkham,Robert Oldroyd,Chris Parker,Mark Emberton,Mark Emberton +16 more
TL;DR: Using MP-MRI to triage men might allow 27% of patients avoid a primary biopsy and diagnosis of 5% fewer clinically insignificant cancers, as well as reduce unnecessary biopsies by a quarter.
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Can Clinically Significant Prostate Cancer Be Detected with Multiparametric Magnetic Resonance Imaging? A Systematic Review of the Literature
Jurgen J. Fütterer,Alberto Briganti,Pieter De Visschere,Mark Emberton,Gianluca Giannarini,Alex Kirkham,Samir S. Taneja,Harriet C. Thoeny,Geert Villeirs,Arnauld Villers +9 more
TL;DR: The diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI) for the detection of clinically significant prostate cancer (PCa) is concluded that mpMRI is able to detect significant PCa and may used to target prostate biopsies.
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High-Resolution MRI of the Anatomy Important in Total Mesorectal Excision of the Rectum
Gina Brown,Alex Kirkham,Geraint T. Williams,M. W. Bourne,Andrew G Radcliffe,Joanne Sayman,Richard Newell,Chummy Sinnatamby,Richard J. Heald +8 more
TL;DR: Anatomic landmarks important to the performance of rectal cancer surgery, in particular the mesorectal fascia, may be defined on MRI and are of potential importance in the staging of tumors, assessing resectability, planning surgery, and selecting patients for preoperative neoadjuvant therapy.
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Reporting Magnetic Resonance Imaging in Men on Active Surveillance for Prostate Cancer: The PRECISE Recommendations—A Report of a European School of Oncology Task Force
Caroline M. Moore,Francesco Giganti,Francesco Giganti,Peter C. Albertsen,Clare Allen,Chris H. Bangma,Alberto Briganti,Peter R. Carroll,Masoom A. Haider,Veeru Kasivisvanathan,Alex Kirkham,Laurence Klotz,Adil Ouzzane,Anwar R. Padhani,Valeria Panebianco,Peter A. Pinto,Philippe Puech,Antti Rannikko,Raphaële Renard-Penna,Karim Touijer,Baris Turkbey,Heinrik van Poppel,Riccardo Valdagni,Jochen Walz,Ivo G. Schoots +24 more
TL;DR: PRECISE recommendations are designed to facilitate the development of a robust evidence database for documenting changes in prostate MRI findings over time of men on active surveillance and to distinguish measurement error and natural variability in MRI appearances from true radiologic progression.
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Transperineal magnetic resonance image targeted prostate biopsy versus transperineal template prostate biopsy in the detection of clinically significant prostate cancer.
Veeru Kasivisvanathan,Robert Dufour,Caroline M. Moore,Hashim U. Ahmed,Mohamed Abd-Alazeez,Susan C. Charman,Alex Freeman,Clare Allen,Alex Kirkham,Jan van der Meulen,Mark Emberton,Mark Emberton +11 more
TL;DR: Prostate biopsy targeted to suspicious lesions on multiparametric magnetic resonance imaging has encouraging rates of detection of clinically significant cancer while also decreasing the detection rate of clinically insignificant cancer.