Alex Rovira

TL;DR: An important red flag is presented in the differential diagnosis of secondary progressive multiple sclerosis: a patient that, after being diagnosed with a clinically isolated syndrome many years ago, seemed to be entering in a secondary progressive course, developing a clinical picture dominated by a progressive gait disturbance.

TL;DR: In this paper, the authors examined the relationship of OC exposure with the risk of a second attack and confirmed Expanded Disability Status Scale of 3.0 using multivariate Cox regression models, adjusted by age, topography of clinically isolated syndrome, oligoclonal bands, baseline brain T2 lesions, body size at menarche, smoking, and disease-modifying treatment (DMT).

TL;DR: T1/T2 has several advantages over other quantitative MRI measures considered markers of myelin density, such as magnetization transfer ratio (MTR), R1 mapping (inverse of the longitudinal relaxation time, T1), myelin water imaging, UTE (ultrashort echo time) or NOODI (neurite orientation dispersion and density imaging): 1 it is based on MRI sequences typically acquired in clinical practice and clinical trials, thus it can be applied in retrospective studies; and the analysis pipeline to get the quantitative maps is relatively simple as mentioned in this paper .

TL;DR: The resonancia magnetica (RM) se considera en la actualidad una tecnica esencial para demostrar the diseminacion especial y temporal of lesiones desmielinizantes that caracterizan the enfermedad as discussed by the authors.

TL;DR: In this article, a prospective study was conducted to characterize MRI features in status epilepticus (SE) patients and determine their association with clinical and electroencephalography (EEG) findings.