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Alexander Birbrair

Researcher at Universidade Federal de Minas Gerais

Publications -  126
Citations -  4528

Alexander Birbrair is an academic researcher from Universidade Federal de Minas Gerais. The author has contributed to research in topics: Stem cell & Medicine. The author has an hindex of 30, co-authored 92 publications receiving 3473 citations. Previous affiliations of Alexander Birbrair include Wake Forest University & Columbia University Medical Center.

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Journal ArticleDOI

Differential cytokine contributions of perivascular haematopoietic stem cell niches

Noboru Asada, +10 more
- 01 Mar 2017 - 
TL;DR: It is shown that the effects of cytokines regulating HSC functions are dependent on the producing cell sources, and distinct contributions of cytokine derived from perivascular cells in separate vascular niches to HSC maintenance are uncovered.
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Type-2 pericytes participate in normal and tumoral angiogenesis.

Alexander Birbrair, +6 more
- 01 Jul 2014 - 
TL;DR: Type-2 pericytes may provide a cellular target susceptible to signaling and pharmacological manipulation in treating malignancy and have the potential to improve blood perfusion in ischemic hindlimbs, indicating their potential for treating isChemic illnesses.
Journal ArticleDOI

Role of Pericytes in Skeletal Muscle Regeneration and Fat Accumulation

Alexander Birbrair, +6 more
- 15 Aug 2013 - 
TL;DR: The results suggest that type-1 and type-2 pericytes contribute to successful muscle regeneration which results from a balance of myogenic and nonmyogenic cells activation.
Journal ArticleDOI

Niche heterogeneity in the bone marrow

Alexander Birbrair, +1 more
- 01 Apr 2016 - 
TL;DR: This review summarizes and evaluates recent advances in the understanding of niche heterogeneity and its influence on HSC function, and assesses the impact of recent advances on cellular cross talk involving HSCs in the BM microenvironment.
Journal ArticleDOI

Type-1 pericytes accumulate after tissue injury and produce collagen in an organ-dependent manner

Alexander Birbrair, +8 more
- 06 Nov 2014 - 
TL;DR: Pericyte subpopulations respond differentially to tissue injury, and the production of collagen by type-1 pericytes is organ-dependent, generating cellular targets for future anti-fibrotic therapeutics.