Z
Zichen Wang
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 434
Citations - 17111
Zichen Wang is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 29, co-authored 70 publications receiving 10382 citations. Previous affiliations of Zichen Wang include Chinese Academy of Sciences & University of Minnesota.
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Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
Maxim V. Kuleshov,Matthew R. Jones,Andrew D. Rouillard,Nicolas F. Fernandez,Qiaonan Duan,Zichen Wang,Simon Koplev,Sherry L. Jenkins,Kathleen M. Jagodnik,Alexander Lachmann,Michael G. McDermott,Caroline D. Monteiro,Gregory W. Gundersen,Avi Ma'ayan +13 more
TL;DR: A significant update to one of the tools in this domain called Enrichr, a comprehensive resource for curated gene sets and a search engine that accumulates biological knowledge for further biological discoveries is presented.
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Enrichr: Interactive and collaborative HTML5 gene list enrichment analysis tool
Edward Y. Chen,Christopher M. Tan,Yan Kou,Qiaonan Duan,Zichen Wang,Gabriela Vaz Meirelles,Neil R. Clark,Avi Ma'ayan +7 more
TL;DR: Enrichr is an easy to use intuitive enrichment analysis web-based tool providing various types of visualization summaries of collective functions of gene lists, and can be embedded into any tool that performs gene list analysis.
Journal ArticleDOI
The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins.
Andrew D. Rouillard,Gregory W. Gundersen,Nicolas F. Fernandez,Zichen Wang,Caroline D. Monteiro,Michael G. McDermott,Avi Ma'ayan +6 more
TL;DR: The Harmonizome is a comprehensive resource of knowledge about genes and proteins that enables researchers to discover novel relationships between biological entities, as well as form novel data-driven hypotheses for experimental validation.
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Single-cell immune landscape of human atherosclerotic plaques
Dawn M. Fernandez,Adeeb Rahman,Nicolas F. Fernandez,Aleksey Chudnovskiy,El-ad David Amir,Letizia Amadori,Nayaab S Khan,Christine K. Wong,Roza Shamailova,Christopher A. Hill,Zichen Wang,Romain Remark,Jennifer Li,Christian Pina,Christopher Faries,Ahmed J. Awad,Ahmed J. Awad,Noah Moss,Johan L.M. Björkegren,Johan L.M. Björkegren,Seunghee Kim-Schulze,Sacha Gnjatic,Avi Ma'ayan,J Mocco,Peter L. Faries,Miriam Merad,Chiara Giannarelli +26 more
TL;DR: Single-cell proteomic and transcriptional profiling of atherosclerotic lesions from human carotid arteries reveals specific features of lesional T cells and macrophages associated with symptomatic disease.
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ChEA3: transcription factor enrichment analysis by orthogonal omics integration.
Alexandra B Keenan,Denis Torre,Alexander Lachmann,Ariel K Leong,Megan L. Wojciechowicz,Vivian Utti,Kathleen M. Jagodnik,Eryk Kropiwnicki,Zichen Wang,Avi Ma'ayan +9 more
TL;DR: The ChEA3 background database contains a collection of gene set libraries generated from multiple sources including TF–gene co-expression from RNA-seq studies, TF–target associations from ChIP-seq experiments, and TF-gree co-occurrence computed from crowd-submitted gene lists, which illuminate general transcription factor properties such as whether the TF behaves as an activator or a repressor.