A
Alexandra A. L. Pennhag
Researcher at Karolinska Institutet
Publications - 6
Citations - 226
Alexandra A. L. Pennhag is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Protein subunit & Mutant. The author has an hindex of 6, co-authored 6 publications receiving 157 citations. Previous affiliations of Alexandra A. L. Pennhag include Science for Life Laboratory.
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Journal ArticleDOI
Compensatory evolution reveals functional interactions between ribosomal proteins S12, L14 and L19.
Sophie Maisnier-Patin,Wilhelm Paulander,Alexandra A. L. Pennhag,Dan I. Andersson,Dan I. Andersson +4 more
TL;DR: A novel functional role for the 50 S ribosomal protein L19 during protein synthesis is revealed, supporting published structural data suggesting that the interaction of L14 and L19 with 16 S rRNA could influence function of the 30 S subunit.
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No evidence for a placental microbiome in human pregnancies at term
Irene Sterpu,Emma Fransson,Luisa W. Hugerth,Juan Du,Marcela Pereira,Liqin Cheng,Sebastian Alexandru Radu,Lorena Calderón-Pérez,Yinghua Zha,Pia Angelidou,Alexandra A. L. Pennhag,Fredrik Boulund,Annika Scheynius,Lars Engstrand,Eva Wiberg-Itzel,Ina Schuppe-Koistinen,Ina Schuppe-Koistinen +16 more
TL;DR: No evidence to support the existence of a placental microbiome is found in a cross-sectional study comparing samples from two groups of full-term births using PCR amplification and sequencing techniques and bacterial culture experiments.
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Changes in Cervical Human Papillomavirus (HPV) Prevalence at a Youth Clinic in Stockholm, Sweden, a Decade After the Introduction of the HPV Vaccine.
Andreas Ährlund-Richter,Liqin Cheng,Yue O. O. Hu,Yue O. O. Hu,Mikaela Svensson,Alexandra A. L. Pennhag,Alexandra A. L. Pennhag,Ramona Gabriela Ursu,Ramona Gabriela Ursu,Linnea Haeggblom,Nathalie Grün,Torbjörn Ramqvist,Lars Engstrand,Lars Engstrand,Tina Dalianis,Juan Du +15 more
TL;DR: Quadrivalent-Gardasil® vaccination has decreased HPV-vaccine type prevalence significantly, however, non- Vaccine HR-HPV types remain high in potentially high-risk women at a youth clinic in Stockholm.
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Evidence of altered mucosa-associated and fecal microbiota composition in patients with Irritable Bowel Syndrome
Johanna Sundin,Imran Aziz,Sofia Nordlander,Annikka V. Polster,Yue O. O. Hu,Luisa W. Hugerth,Alexandra A. L. Pennhag,Lars Engstrand,Hans Törnblom,Magnus Simren,Magnus Simren,Lena Öhman +11 more
TL;DR: It is demonstrated that alterations in the bacterial composition of the sigmoid colon of IBS patients were linked to symptoms and immune activation, and breath tests reflected the mucosa-associated bacterial composition, while there was no evidence for high prevalence of SIBO or small intestinal bacterial alterations in IBS.
Journal ArticleDOI
Caenorhabditis elegans as a Model To Determine Fitness of Antibiotic-Resistant Salmonella enterica Serovar Typhimurium
Wilhelm Paulander,Alexandra A. L. Pennhag,Dan I. Andersson,Dan I. Andersson,Sophie Maisnier-Patin +4 more
TL;DR: The fitness costs determined in the nematode were similar to those measured in mice, validating its use as a simple host model to evaluate bacterial fitness.