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Dan I. Andersson

Researcher at Uppsala University

Publications -  265
Citations -  24659

Dan I. Andersson is an academic researcher from Uppsala University. The author has contributed to research in topics: Antibiotic resistance & Drug resistance. The author has an hindex of 73, co-authored 257 publications receiving 20958 citations. Previous affiliations of Dan I. Andersson include Swedish Institute & Academy of Sciences of the Czech Republic.

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Antibiotic resistance and its cost: is it possible to reverse resistance?

TL;DR: The findings suggest that the fitness costs of resistance will allow susceptible bacteria to outcompete resistant bacteria if the selective pressure from antibiotics is reduced, and that the rate of reversibility will be slow at the community level.
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Selection of resistant bacteria at very low antibiotic concentrations.

TL;DR: It is suggested that the low antibiotic concentrations found in many natural environments are important for enrichment and maintenance of resistance in bacterial populations.
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Microbiological effects of sublethal levels of antibiotics

TL;DR: The ecology of antibiotics and the ability of subinhibitory concentrations to select for bacterial resistance are discussed and the effects of low-level drug exposure on bacterial physiology are considered, including the generation of genetic and phenotypic variability, as well as the able of antibiotics to function as signalling molecules.
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The biological cost of antibiotic resistance

TL;DR: The data available from recent laboratory studies suggest that most, but not all, resistance-determining mutations and accessory elements engender some fitness cost, but those costs are likely to be ameliorated by subsequent evolution.