다중혈관 관상동맥 환자에서 y-문합을 이용하여 양쪽 내흉동맥만을 사용한 우회술의 조기 성적

抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

Bose-Einstein condensation (BEC) has been observed in a dilute gas of sodium atoms. A Bose-Einstein condensate consists of a macroscopic population of the ground state of the system, and is a coherent state of matter. In an ideal gas, this phase transition is purely quantum-statistical. The study of BEC in weakly interacting systems which can be controlled and observed with precision holds the promise of revealing new macroscopic quantum phenomena that can be understood from first principles.

Bose-Einstein condensation in a gas of sodium atoms

Topological photonics is a rapidly emerging field of research in which geometrical and topological ideas are exploited to design and control the behavior of light. Drawing inspiration from the discovery of the quantum Hall effects and topological insulators in condensed matter, recent advances have shown how to engineer analogous effects also for photons, leading to remarkable phenomena such as the robust unidirectional propagation of light, which hold great promise for applications. Thanks to the flexibility and diversity of photonics systems, this field is also opening up new opportunities to realize exotic topological models and to probe and exploit topological effects in new ways. This article reviews experimental and theoretical developments in topological photonics across a wide range of experimental platforms, including photonic crystals, waveguides, metamaterials, cavities, optomechanics, silicon photonics, and circuit QED. A discussion of how changing the dimensionality and symmetries of photonics systems has allowed for the realization of different topological phases is offered, and progress in understanding the interplay of topology with non-Hermitian effects, such as dissipation, is reviewed. As an exciting perspective, topological photonics can be combined with optical nonlinearities, leading toward new collective phenomena and novel strongly correlated states of light, such as an analog of the fractional quantum Hall effect.

Topological Photonics

The term photonic crystals appears because of the analogy between electron waves in crystals and the light waves in artificial periodic dielectric structures. During the recent years the investigation of one-, two-and three-dimensional periodic structures has attracted a widespread attention of the world optics community because of great potentiality of such structures in advanced applied optical fields. The interest in periodic structures has been stimulated by the fast development of semiconductor technology that now allows the fabrication of artificial structures, whose period is comparable with the wavelength of light in the visible and infrared ranges.

http://ieeexplore.ieee.org/iel5/6354/16969/00781867.pdf

Photonic crystals

We produce bimetallic Au:Ag thin films by laser irradiation of the mixed solutions. After several laser scans, granular nanometric films are found to grow with a well-controlled composition, thickness and morphology. By changing laser scanning parameters, the film morphology can be varied from island structures to quasi-periodic arrays. The optical properties of the deposited structures are found to depend on the film composition, thickness and spacing between the particles. The transmittance spectra of the deposited films are shown to be governed by their morphology.

Fractal bimetallic plasmonic structures obtained by laser deposition of colloidal nanoparticles

Bloch oscillations of light in laterally confined Bragg mirrors and multiple coupled microcavities

Bosonic condensates of spin-less non-interacting particles confined on a ring cannot propagate circular periodic currents once rotation symmetry of the system is broken. However a persistent current may appear due to inter-particle interactions exceeding some critical strength. In this up-critical regime breaking of the symmetry between the clockwise and anticlockwise rotations takes place. We consider this symmetry-breaking scenario in the case of a spinor condensate of exciton polaritons trapped on a ring split by a potential barrier. Due to the intrinsic symmetry of the effective spin-orbit interaction which stems from the linear splitting between transverse-electric and transverse-magnetic microcavity modes, the potential barrier blocks the circulating current and imposes linear polarization patterns. On the other hand, circularly polarized polaritons form circular currents propagating in opposite directions with equal absolute values of angular momentum. In the presence of inter-particle interactions, the symmetry of clockwise and anticlockwise currents can be broken spontaneously. We describe several symmetry-breaking scenarios which imply either restoration of the global condensate rotation or the onset of the circular polarization in the symmetry-broken state.

Symmetry breaking and superfluid currents in a split-ring spinor polariton condensate

The possibility of controlling the functional properties of nanostructured thin films of different topology and elemental composition deposited on solid substrates by laser radiation is under our study. Quantum-correlated states that emerge in the deposited granular nanocluster semiconductor/metal structures lead to both hopping/tunneling electroconductivity and specific optical properties. An increase in electrical conductivity (by several orders of magnitude) is observed in experiments depending on the surface and boundary conditions in various topologically organized cluster systems. The high-temperature superconductivity tendency in such nanocluster structures that are both stable and can give rise to different (non-phonon) electron pairing mechanisms is discussed. New optical effects were observed in such topological structures as well.

New challenges of femto-nanophotonics: basic principles and possible applications

We consider two concentric rings formed by bosonic condensates of exciton-polaritons. A circular superfluid flow of polaritons in one of the rings can be manipulated by acting upon the second annular polariton condensate. The complex coupling between the rings with different topological charges triggers nucleation of stable Josephson vortices (JVs) which are revealed as topological defects of the angular dependence of the relative phase between rings. Being dependent on the coupling strength, the structure of the JV governs the difference of the mean angular momenta of the inner and the outer rings. At the vanishing coupling the condensates rotate independently demonstrating no correlations of their winding numbers. At the moderate coupling, the interaction between two condensates tends to equalize their mean angular momenta despite of the mismatch of the winding numbers demonstrating the phenomenology of a drag effect. Above the critical coupling strength the synchronous rotation is established via the phase slip events.

Alexey Kavokin

Papers

Fractal bimetallic plasmonic structures obtained by laser deposition of colloidal nanoparticles

Bloch oscillations of light in laterally confined Bragg mirrors and multiple coupled microcavities

Symmetry breaking and superfluid currents in a split-ring spinor polariton condensate

New challenges of femto-nanophotonics: basic principles and possible applications

Dissipative Josephson vortices in annular polariton fluids