Allison Zemek

TL;DR: Air-liquid interface method propagated patient-derived organoids (PDOs) from >100 human biopsies or mouse tumors in syngeneic immunocompetent hosts as tumor epithelia with native embedded immune cells to enable immuno-oncology investigations within the TME and facilitate personalized immunotherapy testing.

TL;DR: The targeted fungal sequencing assay allowed accurate identification of fungi causing IFD and additionally provided partial-protozoal coverage and diagnostic yield was dependent on the amount of tissue available for testing.

TL;DR: This is the first in-depth profiling of pancreatic neuroendocrine tumors (PanNETs), to the authors' knowledge, that illuminates fundamental biological processes for this class of tumors and demonstrates that MET proto-oncogene activation is important for tumor growth in PanNET xenograft models.

TL;DR: A statistical model is demonstrated using hospital patient data to quantitatively forecast, days in advance, the need for platelet transfusions, and this approach can be leveraged to significantly decrease platelet wastage, and, if adopted nationwide, would save approximately 80 million dollars per year.

TL;DR: Intracapsular tonsillectomy is a suitable option for the surgical treatment of pediatric OSA consequent to its demonstrated efficacy in relieving OSA and its favorable safety profile.