Alois Zauner

TL;DR: The authors evaluated the role of EEAs in human traumatic brain injury in patients who have suffered severe head injury by placing a microdialysis probe into the gray matter along with a ventriculostomy catheter or an intracranial pressure monitor for 4 days.

TL;DR: During the early period after severe head injury, increased lactate levels in brain tissue were reduced by increasing FiO2, which may imply a shift to aerobic metabolism, and increasing PaO2 to higher levels than necessary to saturate hemoglobin appears to improve the O2 supply inbrain tissue.

TL;DR: Brain oxygen pressure, brain carbon dioxide pressure, and brain pH measurements, as well as a microdialysis probe for glucose and lactate analysis, may optimize the management of comatose neurosurgical patients by allowing a fuller understanding of the dynamic factors affecting brain metabolism.

TL;DR: To understand cerebral oxygenation, it is important to understand cerebral blood flow, energy production, ischemia, acidosis, generation of reactive oxygen species, and mitochondrial failure, which provide the basis of knowledge regarding brain bioenergetics and are important topics to understand when developing new approaches to patient care.

TL;DR: With experienced interventionalists, and proper patient selection following the on-label usage guidelines, the use of the Wingspan stent for intracranial atherosclerotic disease demonstrated a low periprocedural complication rate and excellent safety profile.