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Alvin Chandra
Researcher at University of Texas Southwestern Medical Center
Publications - 54
Citations - 960
Alvin Chandra is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 12, co-authored 30 publications receiving 604 citations. Previous affiliations of Alvin Chandra include Parkland Health & Hospital System & Brigham and Women's Hospital.
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Journal ArticleDOI
The relationship of body mass and fat distribution with incident hypertension: observations from the Dallas Heart Study.
Alvin Chandra,Ian J. Neeland,Jarett D. Berry,Colby Ayers,Anand Rohatgi,Sandeep R Das,Amit Khera,Darren K. McGuire,James A. de Lemos,Aslan T. Turer +9 more
TL;DR: Increased visceral adiposity, but not total or subcutaneous adiposity) was robustly associated with incident hypertension, and the mechanisms behind this association are still unclear.
Journal ArticleDOI
Regionally Selective Atrophy After Traumatic Axonal Injury
Matthew A. Warner,Teddy S. Youn,Tommy Davis,Alvin Chandra,Carlos Marquez de la Plata,Carol Moore,Caryn R. Harper,Christopher J. Madden,Jeffrey S. Spence,Roderick W McColl,Michael D. Devous,Richard D. King,Ramon Diaz-Arrastia +12 more
TL;DR: Traumatic axonal injury leads to substantial posttraumatic atrophy that is regionally selective rather than diffuse, and volume loss in certain regions may have prognostic value for functional recovery.
Journal ArticleDOI
Effects of sacubitril/valsartan on physical and social activity limitations in patients with heart failure: a secondary analysis of the PARADIGM-HF trial
Alvin Chandra,Eldrin F. Lewis,Brian Claggett,Akshay S. Desai,Milton Packer,Michael R. Zile,Karl Swedberg,Karl Swedberg,Jean L. Rouleau,Jean L. Rouleau,Victor Shi,Martin Lefkowitz,Tzvetana Katova,John J.V. McMurray,Scott D. Solomon +14 more
TL;DR: In patients with heart failure with reduced ejection fraction, sacubitril/valsartan significantly improved nearly all KCCQ physical and social activities compared with enalapril, with the largest responses in household chores and sexual relationships.
Journal ArticleDOI
Efficacy of Neurohormonal Therapies in Preventing Cardiotoxicity in Patients with Cancer Undergoing Chemotherapy.
Muthiah Vaduganathan,Sameer A. Hirji,Arman Qamar,Navkaranbir S. Bajaj,Ankur Gupta,Vlad G. Zaha,Alvin Chandra,Mark J. Haykowsky,Bonnie Ky,Javid Moslehi,Anju Nohria,Javed Butler,Ambarish Pandey +12 more
TL;DR: Neurohormonal therapies are associated with higher LVEF in follow-up among cancer patients receiving chemotherapy, although absolute changes in LVP are small and may be within inter-test variability, and significant heterogeneity is observed in the treatment effects across studies highlighting the need for larger trials of cardioprotective strategies.
Journal ArticleDOI
Health-related quality of life in heart failure with preserved ejection fraction the PARAGON-HF trial
Alvin Chandra,Muthiah Vaduganathan,Eldrin F. Lewis,Brian Claggett,Adel R. Rizkala,Wenyan Wang,Martin Lefkowitz,Victor Shi,Inder S. Anand,Junbo Ge,Carolyn S.P. Lam,Aldo P. Maggioni,Felipe Martinez,Milton Packer,Marc A. Pfeffer,Burkert Pieske,Margaret M. Redfield,Jean L. Rouleau,Dirk J. van Veldhuisen,Faiez Zannad,Michael R. Zile,John J.V. McMurray,Scott D. Solomon,Scott D. Solomon +23 more
TL;DR: The PARAGON-HF trial as discussed by the authors reported comprehensive baseline health-related quality of life (HRQL) using Kansas City Cardiomyopathy Questionnaire (KCCQ) administered at randomization after active run-in period.