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Amal H. Aly
Researcher at University of Düsseldorf
Publications - 58
Citations - 4266
Amal H. Aly is an academic researcher from University of Düsseldorf. The author has contributed to research in topics: Environmentally friendly & Geopolymer. The author has an hindex of 29, co-authored 51 publications receiving 3671 citations.
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Endophytes and associated marine derived fungi—ecological and chemical perspectives
TL;DR: New insights into fungal-host interaction, chemical communication, and chemo-ecological roles of fungal metabolites, as well as new strategies for bioprospecting are presented.
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Protein Kinase and HDAC Inhibitors from the Endophytic Fungus Epicoccum nigrum
Mustapha El Amrani,Daowan Lai,Abdessamad Debbab,Amal H. Aly,Karsten Siems,Carole Seidel,Michael Schnekenburger,Anthoula Gaigneaux,Marc Diederich,Daniel Feger,Wenhan Lin,Peter Proksch +11 more
TL;DR: Interestingly, compounds 1 and 10 exert mainly cytostatic effects in human lymphoma RAJI and U-937 cell lines.
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Polyketide derivatives of endophytic fungus Pestalotiopsis sp. isolated from the Chinese mangrove plant Rhizophora mucronata
TL;DR: A detailed chemical investigation of the minor metabolites produced by the endophytic fungus Pestalotiopsis sp.
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Pro-Apoptotic and Immunostimulatory Tetrahydroxanthone Dimers from the Endophytic Fungus Phomopsis longicolla
David Rönsberg,Abdessamad Debbab,Attila Mándi,Vera Vasylyeva,Philip Böhler,Björn Stork,Laura H. Engelke,Alexandra Hamacher,Richard Sawadogo,Marc Diederich,Victor Wray,Wenhan Lin,Matthias U. Kassack,Christoph Janiak,Stefanie Scheu,Sebastian Wesselborg,Tibor Kurtán,Amal H. Aly,Peter Proksch +18 more
TL;DR: Preliminary structure-activity studies of isolated compounds and derivatives obtained by semisynthesis hinted at the location of the biaryl axis and the presence of acetyl groups as important structural elements for the biological activity of the studied tetrahydroxanthones.
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Anticancer effect of altersolanol A, a metabolite produced by the endophytic fungus Stemphylium globuliferum, mediated by its pro-apoptotic and anti-invasive potential via the inhibition of NF-κB activity
Marie-Hélène Teiten,Fabienne Mack,Abdessamad Debbab,Amal H. Aly,Mario Dicato,Peter Proksch,Marc Diederich +6 more
TL;DR: Altersolanol A shows cytotoxic, cytostatic, anti-inflammatory and anti-migrative activity against human chronic myeloid K562 leukemia and A549 lung cancer cells in a dose dependent manner without affecting the viability of non cancerous cells.