Amar A. Hosamani

TL;DR: The synthesis and biological evaluation of a new series of pyrrolo[3,2-c]pyridine Mannich bases (7a-v) and molecular docking of the active compounds against glutamate racemase (MurI) and Mtb glutamine synthetase were explained the structure-activity observed in vitro.

TL;DR: In this paper, four homoleptic zinc (1 and 2) and copper (3 and 4) complexes of two Schiff base ligands (L1H and L2H) derived from 2-(3,4-dimethoxyphenyl)ethan-1-amine (5), a dimethyl derivative of dopamine were synthesized.

TL;DR: In this article, a methaniminium hydrazone ligand was used in synthesis of mononuclear Mn(II, Co(II), Ni(II) and Cd(II).

TL;DR: Amongst the tested compounds 5j, 5l and 5q were emerged as good anti-tubercular agents with low cytotoxicity, and the structure-anti TB activity relationship of these derivatives was explained by molecular docking.

TL;DR: In this article, the experimental and theoretical charge density analysis of metformin chloride with high-resolution X-ray diffraction data at low temperature (100 K) was performed and these experimental results were compared with that derived from the corresponding periodic theoretical calculations at the B3LYP/6-31G** level of theory.