Amin Pastaki Khoshbin

TL;DR: The role of macrophages in the lung cancer initiation and progression, pathways regulating their function in lung cancer microenvironment as well as the role of these immune cells in the development of future therapeutic strategies are outlined.

TL;DR: The mechanisms by which myeloid-derived suppressor cells contribute to cancer metastasis are reviewed and the most recognized function is suppressing anti-tumor immune responses are discussed.

TL;DR: In-vitro, in-vivo, and clinical studies are comprehensively reviewed and the following approaches are attempted to unravel the inconsistencies detected: to distinguish local and systemic effects of ghrelin in interpreting its summary clinical role in each cancer; and scrutinizing factors that regulate local effects of Ghrelin and could justify different effects ofghrelin on different cancer cell-lines.

TL;DR: In this paper, the authors provide information on the mechanisms of action of ICIs, review the efficacy results of clinical trials using ICIs for TNBC treatment, and assess the side effects of such drugs.

TL;DR: An 18-year-old man was admitted to evaluate progressive shortness of breath and dry cough of 1-month duration and physical examination revealed he was afebrile and had normal pulse oxygen saturation.