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Amir Azadi
Researcher at Shiraz University of Medical Sciences
Publications - 95
Citations - 3371
Amir Azadi is an academic researcher from Shiraz University of Medical Sciences. The author has contributed to research in topics: Drug delivery & Medicine. The author has an hindex of 18, co-authored 77 publications receiving 2551 citations. Previous affiliations of Amir Azadi include Tehran University of Medical Sciences.
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Hydrogel Nanoparticles in Drug Delivery
TL;DR: Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.
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Pharmacokinetic consequences of pegylation.
TL;DR: The main pharmacokinetic outcomes of pegylation are summarized as changes occurring in overall circulation life-span, tissue distribution pattern, and elimination pathway of the parent drug/particle.
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Brain Delivery of Curcumin Using Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Preparation, Optimization, and Pharmacokinetic Evaluation.
Soroor Sadegh Malvajerd,Amir Azadi,Zhila Izadi,Masoumeh Kurd,Tahereh Dara,Maryam Dibaei,Mohammad Sharif Zadeh,Hamid Akbari Javar,Mehrdad Hamidi +8 more
TL;DR: The DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical scavenging study indicated that preparation processes do not have any significant effect on the antioxidant activity of curcumin.
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A comparison of models for the analysis of the kinetics of drug release from PLGA-based nanoparticles.
TL;DR: A comparative mathematical analysis of drug release from Poly (lactic-co-glycolic acid)–based nanoparticles is offered to suggest a general model explaining multi-mechanistic release they provide to show enough flexibility to describe various release patterns PLGA provides.
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Methotrexate-loaded chitosan nanogels as 'Trojan Horses' for drug delivery to brain: preparation and in vitro/in vivo characterization.
TL;DR: In vivo in intact animals, remarkably higher brain concentrations of methotrexate were achieved with the nanogel formulations in comparison to the free drug (in some cases, more than 10-fold); but there were no significant differences between the surface-modified and unmodified nanogels in all the time points tested.