Amir H. Milani

TL;DR: The results of this study imply that injectable DX microgels have good potential as a future regenerative medicine strategy for restoring the mechanical properties of degenerated load-bearing soft tissue, such as IVDs.

TL;DR: The ability to tune the mechanical properties of the DX microgels using the degree of functionalisation of the parent GM-functionalised microgel, ϕp and pH is demonstrated and it is shown that control of intra- and inter-particle crosslinking can be achieved using preparation conditions.

TL;DR: By improving both the modulus and ductility of the DXmicrogels, the double network approach offers improved potential for future application of DX microgels as implantable biomaterials in high load environments as well as membranes.

TL;DR: In this paper, a simple and scalable, two-step method for preparation of pH-responsive poly(vinylamine) microgels is introduced, where non-aqueous dispersion (NAD) polymerization is used to prepare new monodisperse water-swellable poly(nvinylformamide-co-2-(N-vinyl-formamido)ethyl ether micro gels (PNVF-xNVEE).

TL;DR: A new pH-responsive nanogel probe containing a complementary nonradiative resonance energy transfer (NRET) fluorophore pair is investigated and its ability to act as a versatile probe of network-related changes in three hydrogels demonstrated.