Arrays of ultrasmall and uniform carbon nanodots (CDs) are of pronounced interest for applications in optical devices. Herein, we describe a low-temperature calcination approach with rather inexpensive reactants. After glucose molecules had been loaded into the pores of metal–organic frameworks (MOFs), well-defined CD arrays were produced by heating to 200 °C. The size and spacing of the CDs could be controlled by the choice of templating MOF: HKUST-1, ZIF-8, or MIL-101. The sizes of the obtained CDs were approximately 1.5, 2.0, and 3.2 nm, which are close to the corresponding MOF pores sizes. The CD arrays exhibited interesting photophysical properties, including photoluminescence with tunable emission and pronounced nonlinear optical (NLO) effects. The NLO properties of the obtained CD arrays were significantly different from those of a CD suspension, thus indicating the existence of collective phenomena.

MOF-Templated Synthesis of Ultrasmall Photoluminescent Carbon-Nanodot Arrays for Optical Applications

Indanes and indenes are among the most important carbocycles. Many indane and indene derivatives have shown important pharmacological activities, and the indane and indene nuclei are structural motifs present in several natural products of biological relevance. In spite of their importance, only a few reviews on their preparation methods have appeared so far in the literature, the most recent ones being published about ten years ago. The present Review is aimed at filling this gap, presenting some of the most important and innovative approaches to indanes and indenes that have been published in the course of the last ten years (coverage: from 2005 to May, 2015).

Recent Advances in the Synthesis of Indanes and Indenes

Fluorinated pyrazoles play an important role in medicinal chemistry, drug discovery, agrochemistry, coordination chemistry, and organometallic chemistry. Since the early 1990s, their popularity has grown exponentially. Moreover, more than 50% of all contributions on the topic have been published in the last 5 years. In this review, analysis of novel synthetic approaches to fluorinated pyrazoles that appeared in recent years is performed. A particular emphasis is devoted to a detailed consideration of reaction mechanisms. In addition, the reasons that have led to the ever-increasing popularity of fluorinated pyrazoles in various areas of science are discussed. At the end of the review, several potentially interesting but yet mostly unknown classes of fluorinated pyrazoles are outlined.

Fluorinated Pyrazoles: From Synthesis to Applications.

Herein, we report a greener protocol for the synthesis of 3-Se/S-indoles and imidazo[1,2-a]pyridines through direct C(sp2 )-H bond chalcogenation of heteroarenes with half molar equivalents of different dichalcogenides, using KIO3 as a non-toxic, easy-to-handle catalyst and a stoichiometric amount of glycerol. The reaction features are high yields, based on atom economy, easy performance on gram-scale, metal- and solvent-free conditions as well as applicability to different types of N-heteroarenes.

Direct, Metal-free C(sp2 )-H Chalcogenation of Indoles and Imidazopyridines with Dichalcogenides Catalysed by KIO3.

Abstract A mild and selective C(sp3)−H aerobic oxidation enabled by decatungstate photocatalysis has been developed. The reaction can be significantly improved in a microflow reactor enabling the safe use of oxygen and enhanced irradiation of the reaction mixture. Our method allows for the oxidation of both activated and unactivated C−H bonds (30 examples). The ability to selectively oxidize natural scaffolds, such as (−)‐ambroxide, pregnenolone acetate, (+)‐sclareolide, and artemisinin, exemplifies the utility of this new method.

Selective sp3 C–H aerobic oxidation enabled by decatungstate photocatalysis in flow

Strategic evolution in transition metal-catalyzed directed C–H bond activation and future directions

Overview of Regioselective and Stereoselective Catalytic Hydroboration of Alkynes

A superacid promoted one-pot process for the efficient synthesis of indanones is presented. This process enabled the formation of a dual C–C bond between aryl isopropyl ketones and benzaldehydes. Interestingly, when the reaction was performed between acetophenones and benzaldehydes, it was impeded just after the aldol condensation and resulted in the corresponding chalcones.

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Amrita Das

Papers

Strategic evolution in transition metal-catalyzed directed C–H bond activation and future directions

Overview of Regioselective and Stereoselective Catalytic Hydroboration of Alkynes

An efficient synthesis of highly substituted indanones and chalcones promoted by superacid

The Directing Group: A Tool for Efficient and Selective C–F Bond Activation

Boronic Acid Accelerated Three-Component Reaction for the Synthesis of α-Sulfanyl-Substituted Indole-3-acetic Acids