Amy B. Knudsen

TL;DR: Two independent microsimulation modeling groups from the Cancer Intervention and Surveillance Modeling Network (CISNET), funded by the National Cancer Institute, used a comparative modeling approach to compare life-years gained relative to resource use of different strategies for colorectal cancer screening.

TL;DR: This microsimulation modeling study of a previously unscreened population undergoing CRC screening that assumed 100% adherence identified a set of model-recommendable strategies that provide similar life-years gained (LYG) and a comparable balance between LYG and screening burden.

TL;DR: In this paper, a cost-effectiveness analysis of different colorectal cancer screening methods was conducted to determine the preferred method from a costeffectiveness point of view, and the results showed that the screening tests of stool DNA testing, computed tomographic colonography and capsule endoscopy were not yet cost-effective compared with the established screening options.

TL;DR: There was agreement among studies that the newly developed screening tests of stool DNA testing, computed tomographic colonography, and capsule endoscopy were not yet cost-effective compared with the established screening options.

TL;DR: Prevention of prescription opioid misuse alone is projected to have a modest effect on lowering opioid overdose deaths in the near future, and multipronged approach is needed to dramatically change the course of the epidemic.