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Amy Xiao
Researcher at Massachusetts Institute of Technology
Publications - 17
Citations - 1596
Amy Xiao is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Wastewater & Population. The author has an hindex of 6, co-authored 11 publications receiving 720 citations.
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Journal ArticleDOI
SARS-CoV-2 Titers in Wastewater Are Higher than Expected from Clinically Confirmed Cases
Fuqing Wu,Jianbo Zhang,Amy Xiao,Xiaoqiong Gu,Wei Lin Lee,Federica Armas,Kathryn M. Kauffman,William P. Hanage,Mariana Matus,Newsha Ghaeli,Noriko Endo,Claire Duvallet,Mathilde Poyet,Katya Moniz,Alex D. Washburne,Timothy B. Erickson,Timothy B. Erickson,Peter R. Chai,Peter R. Chai,Janelle R. Thompson,Eric J. Alm +20 more
TL;DR: A laboratory protocol to quantify viral titers in raw sewage via qPCR analysis and validate results with sequencing analysis suggests that the number of positive cases estimated from wastewater viral titer is orders of magnitude greater than the numberof confirmed clinical cases and therefore may significantly impact efforts to understand the case fatality rate and progression of disease.
Posted ContentDOI
SARS-CoV-2 titers in wastewater are higher than expected from clinically confirmed cases
Fuqing Wu,Amy Xiao,Jianbo Zhang,Xiaoqiong Gu,Wei Lin Lee,Kathryn M. Kauffman,William P. Hanage,Mariana Matus,Newsha Ghaeli,Noriko Endo,Claire Duvallet,Katya Moniz,Timothy B. Erickson,Peter R. Chai,Janelle R. Thompson,Eric J. Alm +15 more
TL;DR: Wastewater surveillance at a major urban treatment facility in Massachusetts found the presence of SARS-CoV-2 at high titers in the period from March 18 - 25 using RT-qPCR, and the identity of the PCR product was confirmed by direct DNA sequencing.
Posted ContentDOI
SARS-CoV-2 titers in wastewater foreshadow dynamics and clinical presentation of new COVID-19 cases
Fuqing Wu,Amy Xiao,Jianbo Zhang,Katya Moniz,Noriko Endo,Federica Armas,Richard Bonneau,Megan A. Brown,Mary Bushman,Peter R. Chai,Peter R. Chai,Claire Duvallet,Timothy B. Erickson,Timothy B. Erickson,Katelyn Foppe,Newsha Ghaeli,Xiaoqiong Gu,William P. Hanage,Katherine H. Huang,Wei Lin Lee,Mariana Matus,Kyle A. McElroy,Jonathan Nagler,Steven F Rhode,Mauricio Santillana,Mauricio Santillana,Joshua A. Tucker,Stefan Wuertz,Shijie Zhao,Janelle R. Thompson,Eric J. Alm +30 more
TL;DR: In this article, the authors used longitudinal wastewater analysis to track SARS-CoV-2 dynamics in wastewater at a major urban wastewater treatment facility in Massachusetts, between early January and May 2020.
Journal ArticleDOI
SARS-CoV-2 RNA concentrations in wastewater foreshadow dynamics and clinical presentation of new COVID-19 cases.
Fuqing Wu,Amy Xiao,Jianbo Zhang,Katya Moniz,Noriko Endo,Federica Armas,Richard Bonneau,Megan A. Brown,Mary Bushman,Peter R. Chai,Peter R. Chai,Claire Duvallet,Timothy B. Erickson,Timothy B. Erickson,Katelyn Foppe,Newsha Ghaeli,Xiaoqiong Gu,William P. Hanage,Katherine H. Huang,Wei Lin Lee,Mariana Matus,Kyle A. McElroy,Jonathan Nagler,Steven F Rhode,Mauricio Santillana,Mauricio Santillana,Joshua A. Tucker,Stefan Wuertz,Shijie Zhao,Janelle R. Thompson,Eric J. Alm +30 more
TL;DR: In this article, the authors quantify the SARS-CoV-2 concentration and track its dynamics in wastewater at a major urban wastewater treatment facility in Massachusetts, between early January and May 2020.
Journal ArticleDOI
Wastewater surveillance of SARS-CoV-2 across 40 U.S. states from February to June 2020.
Fuqing Wu,Amy Xiao,Jianbo Zhang,Katya Moniz,Noriko Endo,Federica Armas,Mary Bushman,Peter R. Chai,Claire Duvallet,Timothy B. Erickson,Katelyn Foppe,Newsha Ghaeli,Xiaoqiong Gu,William P. Hanage,Katherine H. Huang,Wei Lin Lee,Kyle A. McElroy,Steven F Rhode,Mariana Matus,Stefan Wuertz,Janelle R. Thompson,Eric J. Alm +21 more
TL;DR: In this paper, the authors describe a nationwide campaign to monitor SARS-CoV-2 in the wastewater of 159 counties in 40 U.S. states from February 18 to June 2, 2020.