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Ana García-Martínez
Researcher at University of Barcelona
Publications - 58
Citations - 2824
Ana García-Martínez is an academic researcher from University of Barcelona. The author has contributed to research in topics: Giant cell arteritis & Vasculitis. The author has an hindex of 26, co-authored 53 publications receiving 2412 citations. Previous affiliations of Ana García-Martínez include Cleveland Clinic Lerner College of Medicine & National Institutes of Health.
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Journal ArticleDOI
Large vessel involvement in biopsy-proven giant cell arteritis: prospective study in 40 newly diagnosed patients using CT angiography
Sergio Prieto-González,Pedro Arguis,Ana García-Martínez,Georgina Espígol-Frigolé,Itziar Tavera-Bahillo,Montserrat Butjosa,Marcelo Sánchez,José Hernández-Rodríguez,Josep M. Grau,Maria C. Cid +9 more
TL;DR: CTA-defined LVV occurs in two-thirds of patients with GCA at the time of diagnosis and aortic dilation is already present in 15%.
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Tissue production of pro-inflammatory cytokines (IL-1β, TNFα and IL-6) correlates with the intensity of the systemic inflammatory response and with corticosteroid requirements in giant-cell arteritis
José Hernández-Rodríguez,Marta Segarra,C. Vilardell,M. Sánchez,Ana García-Martínez,M. J. Esteban,Carme Queralt,Grau Jm,Alvaro Urbano-Márquez,A Palacín,D. Colomer,Maria C. Cid +11 more
TL;DR: GCA patients with a strong systemic inflammatory response, who have been previously shown to be more resistant to corticosteroid therapy, have elevated tissue expression of proinflammatory cytokines IL-1beta, TNFalpha and IL-6.
Journal ArticleDOI
Development of aortic aneurysm/dilatation during the followup of patients with giant cell arteritis: a cross-sectional screening of fifty-four prospectively followed patients
Ana García-Martínez,José Hernández-Rodríguez,Pedro Arguis,Pilar Paredes,Marta Segarra,Ester Lozano,Carlos Nicolau,José Ramírez,Francesc Lomeña,Miguel Josa,Francesca Pons,Maria C. Cid +11 more
TL;DR: The data do not support that aneurysm formation mainly results from persistent detectable disease activity, and additional factors including characteristics of the initial injury or the target tissue may also determine susceptibility to aortic aneurYSm/dilatation.
Journal ArticleDOI
Elevated Production of Interleukin-6 Is Associated With a Lower Incidence of Disease-Related Ischemic Events in Patients With Giant-Cell Arteritis Angiogenic Activity of Interleukin-6 as a Potential Protective Mechanism
José Hernández-Rodríguez,Marta Segarra,C. Vilardell,M. Sánchez,Ana García-Martínez,María-José Esteban,Josep M. Grau,Alvaro Urbano-Marquez,Dolors Colomer,Hynda K. Kleinman,Maria C. Cid +10 more
TL;DR: IL-6 activates a functional program related to angiogenesis that may compensate for ischemia in patients with GCA, and is found to have lower tissue expression and circulating levels of IL-6 than patients with no ischemic events.
Journal ArticleDOI
Relapses in Patients With Giant Cell Arteritis: Prevalence, Characteristics, and Associated Clinical Findings in a Longitudinally Followed Cohort of 106 Patients
Marco A. Alba,Ana García-Martínez,Sergio Prieto-González,Itziar Tavera-Bahillo,Marc Corbera-Bellalta,Ester Planas-Rigol,Georgina Espígol-Frigolé,Montserrat Butjosa,José Hernández-Rodríguez,Maria C. Cid +9 more
TL;DR: Evidence is provided that a relapsing course is associated with higher and prolonged GC requirements and a higher frequency of osteoporosis in GCA.