J
José Hernández-Rodríguez
Researcher at University of Barcelona
Publications - 144
Citations - 5284
José Hernández-Rodríguez is an academic researcher from University of Barcelona. The author has contributed to research in topics: Giant cell arteritis & Vasculitis. The author has an hindex of 40, co-authored 119 publications receiving 4350 citations. Previous affiliations of José Hernández-Rodríguez include Leeds Teaching Hospitals NHS Trust.
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Journal ArticleDOI
Large vessel involvement in biopsy-proven giant cell arteritis: prospective study in 40 newly diagnosed patients using CT angiography
Sergio Prieto-González,Pedro Arguis,Ana García-Martínez,Georgina Espígol-Frigolé,Itziar Tavera-Bahillo,Montserrat Butjosa,Marcelo Sánchez,José Hernández-Rodríguez,Josep M. Grau,Maria C. Cid +9 more
TL;DR: CTA-defined LVV occurs in two-thirds of patients with GCA at the time of diagnosis and aortic dilation is already present in 15%.
Journal ArticleDOI
Tissue production of pro-inflammatory cytokines (IL-1β, TNFα and IL-6) correlates with the intensity of the systemic inflammatory response and with corticosteroid requirements in giant-cell arteritis
José Hernández-Rodríguez,Marta Segarra,C. Vilardell,M. Sánchez,Ana García-Martínez,M. J. Esteban,Carme Queralt,Grau Jm,Alvaro Urbano-Márquez,A Palacín,D. Colomer,Maria C. Cid +11 more
TL;DR: GCA patients with a strong systemic inflammatory response, who have been previously shown to be more resistant to corticosteroid therapy, have elevated tissue expression of proinflammatory cytokines IL-1beta, TNFalpha and IL-6.
Journal ArticleDOI
Diagnosis and classification of polyarteritis nodosa.
TL;DR: A recent consensus algorithm for the classification of PAN has attempted to overcome some of the caveats of the 1990 American College of Rheumatology classification criteria which have proven to be unsatisfactory, and has also confirmed the low prevalence of PAN compared to other systemic necrotizing vasculitides.
Journal ArticleDOI
Development of aortic aneurysm/dilatation during the followup of patients with giant cell arteritis: a cross-sectional screening of fifty-four prospectively followed patients
Ana García-Martínez,José Hernández-Rodríguez,Pedro Arguis,Pilar Paredes,Marta Segarra,Ester Lozano,Carlos Nicolau,José Ramírez,Francesc Lomeña,Miguel Josa,Francesca Pons,Maria C. Cid +11 more
TL;DR: The data do not support that aneurysm formation mainly results from persistent detectable disease activity, and additional factors including characteristics of the initial injury or the target tissue may also determine susceptibility to aortic aneurYSm/dilatation.
Journal ArticleDOI
Elevated Production of Interleukin-6 Is Associated With a Lower Incidence of Disease-Related Ischemic Events in Patients With Giant-Cell Arteritis Angiogenic Activity of Interleukin-6 as a Potential Protective Mechanism
José Hernández-Rodríguez,Marta Segarra,C. Vilardell,M. Sánchez,Ana García-Martínez,María-José Esteban,Josep M. Grau,Alvaro Urbano-Marquez,Dolors Colomer,Hynda K. Kleinman,Maria C. Cid +10 more
TL;DR: IL-6 activates a functional program related to angiogenesis that may compensate for ischemia in patients with GCA, and is found to have lower tissue expression and circulating levels of IL-6 than patients with no ischemic events.