Ana Maria Oliveira Brett

TL;DR: In this paper, a reverse phase HPLC with electrochemical detection (RP•HPLC•ED) was used to detect anthocyanins, flavonoid compounds present in grapes and wines.

TL;DR: In order to better understand the adsorption mechanism of nucleic acids at electrode surface, MAC Mode atomic force microscopy (MAC Mode AFM) was used in this article to investigate the adaption of a 10-base synthetic oligodeoxynucleotide (ODN) with the sequence 5 -CTTTTTCTTT-3, containing only pyrimidinic bases, onto a highly oriented pyrolytic graphite (HOPG) electrode.

TL;DR: In this article, graphite-polyurethane composite electrodes with different graphite weight percentages were morphologically studied by atomic force microscopy (AFM) and voltammetry.

TL;DR: The search for drugs with cytostatic activity and with better pharmacokinetic features led to the synthesis of Navelbine (5'-noranhydrovinblastine) which is a structural modification of antitumour Vinca alkaloids, which has high liposolubility, a lower toxicity and increased antitumours activity.

TL;DR: In this paper , the authors provide an exhaustive review concerning the electrochemical methods of characterization and quantification of different classes of chemotherapeutic alkylating agents (triazenes and hydrazines, nitrosoureas, nitrogen mustards, oxazaphosphorines, alkyls alkane sulfonates and ethylene imines) in standard samples, pharmaceutical formulations and biological matrixes.