Ana Sastre

TL;DR: This report elucidates, for the first time, data about genomic instability in ES, based on CNA and expression profiling, and shows that a genomically unstable group of Ewing's tumours is correlated with a significant poor prognosis.

TL;DR: The hypothesis that cholecystokinin acts as an autocrine growth factor stimulating the proliferation of Ewing cells is supported and therapies targeting CCK could be promising in the treatment of EWing tumors is suggested.

TL;DR: This study will establish which is the “standard regimen” of chemotherapy, taking into account both clinical outcomes and toxicity, and form the chemotherapy backbone for future interventional studies where the authors may want to add new targeted agents.

TL;DR: The warning signs of primary and secondary IDs in paediatric and adult patients with oncohaematological manifestations are defined to highlight the importance of an early diagnosis and treatment to avoid complications.

TL;DR: Although this treatment achieved a good control of viral reactivations, an unexpectedly high rate of limbic encephalitis due to human herpesvirus-6 (HHV-6; 8 cases) was observed, characteristically, the infection appeared early in almost all patients, just after the engraftment.