Anastasia S. Mihailidou

TL;DR: The present study, the first to report 24-hour HR monitoring in the early weeks of bereavement, has demonstrated increased HR and altered autonomic function that might contribute to the increased cardiovascular events in early bereavement.

TL;DR: It is demonstrated, for the first time, that sex steroids regulate autophagy during myocardial infarction and shows that a novel mechanism of action for androgens during I-R is down-regulation of antiapoptotic protein Bcl-xL (B cell lymphoma-extra large), a key controller for cross talk between Autophagy and apoptosis, shifting the balance toward apoptosis and leading to aggravated cardiac damage.

TL;DR: It is concluded that chronic amiodarone treatment reduces overall Na(+)-K+ pump capacity in cardiac ventricular myocytes, and an amodarone-induced inhibition of the hyperpolarizing Na( +)-K- pump current may contribute to the action potential prolongation observed during treatment with this drug.

TL;DR: Treatment with lovastatin reduces Na(+)-K(+) pump activity and abundance in rabbit and rat sarcolemma and causes statistically significant reductions in I(p), myocardial and skeletal muscle K-dependent p-NPPase activity and 3H-ouabain binding in the myocardium and skeletal Muscle.

TL;DR: It is concluded that among mildly hypertensive individuals, almost half can lower systolic pressure at will for short periods, independent of the real or placebo nature of the feedback signal, and further exploration is needed to determine whether specific components of the placebo effect can be delineated.