D
David J. Handelsman
Researcher at University of Sydney
Publications - 654
Citations - 31170
David J. Handelsman is an academic researcher from University of Sydney. The author has contributed to research in topics: Androgen & Testosterone. The author has an hindex of 90, co-authored 612 publications receiving 27518 citations. Previous affiliations of David J. Handelsman include Monash Institute of Medical Research & University of Washington.
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Journal ArticleDOI
Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes.
Danijela Gnjidic,Sarah N. Hilmer,Sarah N. Hilmer,Fiona M. Blyth,Fiona M. Blyth,Vasi Naganathan,Vasi Naganathan,Louise M. Waite,Louise M. Waite,Markus J. Seibel,Markus J. Seibel,Andrew J. McLachlan,Andrew J. McLachlan,Robert G. Cumming,Robert G. Cumming,David J. Handelsman,David J. Handelsman,David G. Le Couteur,David G. Le Couteur +18 more
TL;DR: The study supports the use of five or more medications in the current definition of polypharmacy to estimate the medication-related adverse effects for frailty, disability, mortality, and falls.
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Androgens and cardiovascular disease.
TL;DR: The commonality of risk factor patterns and mechanisms suggests that the efficacy of antiatherogenic therapy is an important challenge with the potential to enhance men's motivation for prevention and treatment of cardiovascular diseases.
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Loss of muscle strength, mass (sarcopenia), and quality (specific force) and its relationship with functional limitation and physical disability: the Concord Health and Ageing in Men Project.
Noran Naqiah Hairi,Robert G. Cumming,Vasi Naganathan,David J. Handelsman,David G. Le Couteur,Helen Creasey,Louise M. Waite,Markus J. Seibel,Philip N. Sambrook +8 more
TL;DR: To determine the association between loss of muscle strength, mass, and quality and functional limitation and physical disability in older men, a large number of men aged 60 and over are surveyed.
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Induction of spermatogenesis by androgens in gonadotropin-deficient (hpg) mice.
TL;DR: It is concluded that androgens, acting through the androgen receptor without need for aromatization, initiate qualitatively complete spermatogenesis in the mouse, including fertile sperm despite low intratesticular androgen levels and the absence of blood FSH levels.
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Contraceptive efficacy of testosterone-induced azoospermia in normal men
G-Y Zhang,G-Z Li,Fcw Wu,Hwg Baker,X-H Wang,J C Soufir,Ilpo Huhtaniemi,C. A. Paulsen,C Gottlieb,David J. Handelsman,Tmm Farley,C Hazelden,A Peregoudov,Gmh Waites +13 more
TL;DR: Results suggest that intermittent increased prolactin secretion may augment ovarian response to gonadotropins in metoclopramide-treated cycles as compared with control cycles.