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Anca Sima
Publications - 15
Citations - 1017
Anca Sima is an academic researcher. The author has contributed to research in topics: Cholesterol & Transcytosis. The author has an hindex of 8, co-authored 15 publications receiving 877 citations.
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Journal ArticleDOI
Statins: mechanism of action and effects
Camelia S. Stancu,Anca Sima +1 more
TL;DR: Being the most efficient hypolipidemic compounds that have reduced the rate of mortality in coronary patients, statins reduce significantly the incidence of coronary events, both in primary and secondary prevention.
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Endothelial transcytosis in health and disease
TL;DR: Understanding of the molecular machinery that precisely guides caveolae through the cells so as to reach the target membrane (fission, docking, and fusion) will assist in the design of pathways that, by manipulating the physiological route of Caveolae, will carry molecules of choice at controlled concentrations to precise destinations.
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Apolipoprotein E polymorphism--a risk factor for metabolic syndrome.
TL;DR: Correlations of apoE genotypes with these markers indicate that the ɛ4 allele is an independent risk factor for metabolic syndrome.
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Homozygous familial hypercholesterolemia: specific indication for domino liver transplantation.
Irinel Popescu,Maya Simionescu,Tulbure D,Anca Sima,Cosmin Catana,Loredan S. Niculescu,Nicolae Hancu,Liana Gheorghe,Mariana Mihaila,Silviu Ciurea,Viorica Vidu +10 more
TL;DR: Domino transplantation can be efficiently used in a patient with marginal indications for transplantation using a liver from a patients with FHC, and the slightly elevated serum cholesterol level in the recipient may be explained by the normal function of extrahepatic LDL-R.
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Apolipoprotein A-V gene polymorphisms in subjects with metabolic syndrome.
TL;DR: The results demonstrate an independent risk for −1.131T>C APOA5 gene polymorphisms in the development of metabolic syndrome.