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Andrea Aguirre

Researcher at Wilmington University

Publications -  5
Citations -  245

Andrea Aguirre is an academic researcher from Wilmington University. The author has contributed to research in topics: Mitochondrial DNA & Prostate cancer. The author has an hindex of 4, co-authored 5 publications receiving 236 citations.

Papers
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Journal ArticleDOI

The pseudo-mitochondrial genome influences mistakes in heteroplasmy interpretation

Ryan Parr, +8 more
- 21 Jul 2006 - 
TL;DR: These findings suggest that mitochondrial genome disease-associated biomarkers must be rigorously authenticated to preclude any affiliation with paralogous nuclear pseudogenes, and are the first to fully sequence 46 paralogyous nuclear DNA fragments that represent the entire mitochondrial genome.
Journal ArticleDOI

Somatic Mitochondrial DNA Mutations in Prostate Cancer and Normal Appearing Adjacent Glands in Comparison to Age-Matched Prostate Samples without Malignant Histology

Ryan Parr, +13 more
- 01 Jul 2006 - 
TL;DR: It is concluded that mitochondrial genome mutations are an early indicator of malignant transformation in prostate tissue, well before changes in tissue histo-pathology, indicative of prostate cancer, are evident to the pathologist.
Journal ArticleDOI

Mitochondrial Genome Deletion Aids in the Identification of False- and True-Negative Prostate Needle Core Biopsy Specimens

Jennifer Maki, +18 more
- 01 Jan 2008 - 
TL;DR: The usefulness of a 3.4-kb mitochondrial genome deletion (3.4 mtdelta) for molecular definition of benign, malignant, and proximal to malignant (PTM) prostate needle biopsy specimens is reported.
Patent

Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers

Ryan Parr, +8 more
TL;DR: In this paper, methods and kits for detecting mitochondrial DNA deletions for the early detection, diagnosis and progression of prostate cancer, sun exposure and non-melonoma skin cancer are provided.
Patent

Réarrangements et mutations mitochondriales utilisés en tant qu'outil de diagnostic pour la détection de l'exposition au soleil, le cancer de la prostate et d'autres cancers

Ryan Parr, +8 more
TL;DR: Les deletions d'ADN mitochondriales sont utiles for the detection des cancers and de l'exposition au soleil as discussed by the authors, and they can be used for precoce et le diagnostic, de la progression du cancer de la prostate, de lexposition de la soleil and du cancer of la peau non melanique.