Jennifer Maki

TL;DR: These findings suggest that mitochondrial genome disease-associated biomarkers must be rigorously authenticated to preclude any affiliation with paralogous nuclear pseudogenes, and are the first to fully sequence 46 paralogyous nuclear DNA fragments that represent the entire mitochondrial genome.

TL;DR: It is concluded that mitochondrial genome mutations are an early indicator of malignant transformation in prostate tissue, well before changes in tissue histo-pathology, indicative of prostate cancer, are evident to the pathologist.

TL;DR: The usefulness of a 3.4-kb mitochondrial genome deletion (3.4 mtdelta) for molecular definition of benign, malignant, and proximal to malignant (PTM) prostate needle biopsy specimens is reported.

TL;DR: In this paper, methods and kits for detecting mitochondrial DNA deletions for the early detection, diagnosis and progression of prostate cancer, sun exposure and non-melonoma skin cancer are provided.

TL;DR: NAF is demonstrated that NAF is a suitable material for mtDNA sequence analysis using the rapid and reliable MCv2, and somatic mtDNA mutations present in NAF of women with benign breast diseases could potentially be used as risk factors for progression to breast cancer.