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Andrea B. Zepeda
Researcher at University of La Frontera
Publications - 20
Citations - 842
Andrea B. Zepeda is an academic researcher from University of La Frontera. The author has contributed to research in topics: Oxidative stress & Pichia pastoris. The author has an hindex of 12, co-authored 20 publications receiving 674 citations. Previous affiliations of Andrea B. Zepeda include Arturo Prat University.
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Journal ArticleDOI
The hypoxic testicle: physiology and pathophysiology.
Juan G. Reyes,Jorge G. Farías,Sebastián Henríquez-Olavarrieta,Eva Madrid,Mario Párraga,Andrea B. Zepeda,Ricardo D. Moreno +6 more
TL;DR: It is suggested that conditions such as germ cell apoptosis and DNA damage are common features in hypoxia and varicocele and testicular torsion and oxidative damage seems to be present in these conditions during the initiation stages of germ cell damage and apoptosis.
Journal ArticleDOI
Antioxidant Therapeutic Strategies for Cardiovascular Conditions Associated with Oxidative Stress
Jorge G. Farías,Víctor Molina,Rodrigo A Carrasco,Andrea B. Zepeda,Elías Figueroa,Elías Figueroa,Pablo Letelier,Pablo Letelier,Rodrigo L. Castillo +8 more
TL;DR: The participation of OS in the pathophysiology of cardiovascular conditions such as myocardial infarction, anthracycline cardiotoxicity and congenital heart disease is described, giving support for novel pharmacological therapies such as omega 3 fatty acids, non-selective betablockers and microRNAs.
Journal ArticleDOI
Cellular and molecular mechanisms in the hypoxic tissue: role of HIF-1 and ROS.
Andrea B. Zepeda,Adalberto Pessoa,Rodrigo L. Castillo,Carolina A. Figueroa,Victor M Pulgar,Victor M Pulgar,Jorge G. Farías +6 more
TL;DR: New developments in HIF‐mediated O2 sensing mechanisms and their interactions with reactive oxygen species–generating pathways in normal and abnormal physiology are summarized.
Journal ArticleDOI
Applications of recombinant Pichia pastoris in the healthcare industry
Daniel Weinacker,Claudia Rabert,Andrea B. Zepeda,Carolina A. Figueroa,Adalberto Pessoa,Jorge G. Farías +5 more
TL;DR: The attempt of this review is to embrace several research lines that have adopted Pichia pastoris as their expression system to produce a protein on an industrial scale in the health care industry.
Journal ArticleDOI
Oxidative stress in rat testis and epididymis under intermittent hypobaric hypoxia: protective role of ascorbate supplementation.
Jorge G. Farías,Mariela Puebla,Alejandro Acevedo,Pablo Jose Tapia,Eduardo Gutierrez,Andrea B. Zepeda,Gloria M. Calaf,Camila Juantok,Juan G. Reyes +8 more
TL;DR: In conclusion, AA was capable of decreasing oxidative stress in testis and epididymis under IHH, and this protection by AA of the IHH-induced lipid peroxidation can be explained in part by the preservation of glutathione reductase activity in these organs.