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Andrea Cossarizza
Researcher at University of Modena and Reggio Emilia
Publications - 487
Citations - 34586
Andrea Cossarizza is an academic researcher from University of Modena and Reggio Emilia. The author has contributed to research in topics: Immune system & Mitochondrion. The author has an hindex of 78, co-authored 448 publications receiving 30168 citations. Previous affiliations of Andrea Cossarizza include Academy for Urban School Leadership & University of Urbino.
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Decreased mitochondrial DNA content in subcutaneous fat from HIV-infected women taking antiretroviral therapy as measured at delivery.
Milena Nasi,Marcello Pinti,Elisabetta Chiesa,Simona Fiore,Serena Manzini,Cinzia Del Giovane,Roberto D'Amico,N Palai,Carlo Campatelli,Francesca Sabbatini,Marianna Roccio,Cecilia Tibaldi,Giulia Masuelli,Cristina Mussini,Enrico Ferrazzi,Antonella d'Arminio Monforte,Andrea Cossarizza +16 more
TL;DR: In subcutaneous tissue from women taking NRTI-based antiretroviral regimens, a significant decrease of mtDNA content was observed, compared with uninfected women not on antiviral treatment and a significant correlation was noted between mt DNA content and HDL cholesterol and triglycerides.
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Reliable and accurate CD4+ T cell count and percent by the portable flow cytometer CyFlow MiniPOC and "CD4 Easy Count Kit-Dry", as revealed by the comparison with the gold standard dual platform technology.
Milena Nasi,Sara De Biasi,Elena Bianchini,Lara Gibellini,Marcello Pinti,Tiziana Scacchetti,Tommaso Trenti,Vanni Borghi,Cristina Mussini,Andrea Cossarizza +9 more
TL;DR: The cost-effective CyFlow MiniPOC produces rapid, reliable and accurate results that are fully comparable with those from highly expensive dual platform systems.
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Markers of cell death-activation in lymphocytes of vertically HIV-infected children naive to highly active antiretroviral therapy: The role of age
Alessandra Viganò,Marcello Pinti,Milena Nasi,Laura Moretti,Fiorella Balli,Cristina Mussini,Dorella Bricalli,Natascia Sala,Roberto Bugarini,Stefano Vella,Nicola Principi,Andrea Cossarizza +11 more
TL;DR: Changes in PBL phenotype, increased expression of CD95, and high sensitivity to apoptosis suggest that a precocious aging of the immune system occurs in HIV-infected children.
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Analysis of inflammasomes and antiviral sensing components reveals decreased expression of NLRX1 in HIV-positive patients assuming efficient antiretroviral therapy.
Milena Nasi,Sara De Biasi,Elena Bianchini,Margherita Digaetano,Marcello Pinti,Lara Gibellini,Simone Pecorini,Gianluca Carnevale,Giovanni Guaraldi,Vanni Borghi,Cristina Mussini,Andrea Cossarizza +11 more
TL;DR: Compared with controls, HIV-positive patients showed significantly lower mRNA levels of the mitochondrial protein NLRX1, which plays a key role in regulating apoptotic cell death; main PBMC subpopulations behave in a similar manner.
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HIV-1 Infection and the Aging of the Immune System: Facts, Similarities and Perspectives
Sara De Biasi,Marcello Pinti,Milena Nasi,Lara Gibellini,Linda Bertoncelli,Serena Manzini,Cristina Mussini,Andrea Cossarizza +7 more
TL;DR: The similarities that exist between immunological changes present during the physiological aging process and HIV infection will be underline.