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Andrea Cossarizza

Researcher at University of Modena and Reggio Emilia

Publications -  487
Citations -  34586

Andrea Cossarizza is an academic researcher from University of Modena and Reggio Emilia. The author has contributed to research in topics: Immune system & Mitochondrion. The author has an hindex of 78, co-authored 448 publications receiving 30168 citations. Previous affiliations of Andrea Cossarizza include Academy for Urban School Leadership & University of Urbino.

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Exposure to low-frequency pulsed electromagnetic fields increases mitogen-induced lymphocyte proliferation in Down's syndrome.

TL;DR: The age-related effect of PEMFs on DS lymphocytes demonstrates that age must be considered a major variable when studies on DS are performed, and confirms that DS must be regarded as a syndrome of accelerated aging.
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Decreased apoptosis of bone marrow progenitor cells in HIV-1-infected patients during highly active antiretroviral therapy.

TL;DR: The effects of highly active antiretroviral therapy on apoptosis of CD34+ stem cells derived from the bone marrow of HIV-1-infected patients are evaluated, and decreased Fas expression on progenitor cells is observed, in parallel with the diminution of TNF-alpha levels and the amelioration of clonogenic parameters.
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Involvement of CD45 in dexamethasone- and heat shock-induced apoptosis of rat thymocytes.

TL;DR: It is reported here that apoptosis of rat thymocytes after in vitro dexamethasone and heat shock treatment was accompanied by an early significative increase of cells expressing CD45RC, the high molecular weight isoform of CD45 molecule, suggesting that CD45 modulation can be added to the list of early molecular events.
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Mitochondrial Proteases as Emerging Pharmacological Targets.

TL;DR: Six mitochondrial proteases are focused on, namely CLPP, HTRA2 and LONP1, by analysing the current knowledge about their functions, their involvement in the pathogenesis of human diseases, and the compounds currently available for inhibiting their functions.
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Human Natural Killer Cytotoxic Activity is not Affected by in Vitro Exposure to 50-Hz Sinusoidal Magnetic Fields

TL;DR: The results of both laboratories suggest that 50-Hz sinusoidal magnetic fields with flux densities up to 10 mT do not affect the cytotoxic activity of human NK cells.