Andrea Ferrigno

TL;DR: MP at 20°C improves cell survival and leads to a marked improvement in hepatic preservation of steatotic livers as compared with cold storage, substantiated by better morphology, higher glycogen content, and lower reactive oxygen species production by sinusoidal cells in Steatotic liver submitted to MP at20°C versus cold storage.

TL;DR: The multiple GSH functions will be described, as well as the importance of GSH compartmentalization into distinct subcellular pools and inter-organ transfer, and the close relationship existing between GSH content and the pathogenesis of liver disease, such as non-alcoholic fatty liver disease (NAFLD, alcoholic liver disease) and chronic cholestatic injury.

TL;DR: All the changes observed for cell autofluorescence properties were consistent with the complex metabolic pathways providing for energy supply.

TL;DR: It is demonstrated that melatonin improves significantly the restoration of liver function after cold‐storage and reperfusion and in a dose‐dependent manner.

TL;DR: Machine perfusion at 20°C improves cell survival and gives a better-quality of preservation for livers obtained from NHBDs and may provide a new method for the successful utilization of marginal livers.