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Andrea Glasauer
Researcher at Northwestern University
Publications - 5
Citations - 1675
Andrea Glasauer is an academic researcher from Northwestern University. The author has contributed to research in topics: Cancer cell & Cancer. The author has an hindex of 4, co-authored 5 publications receiving 1366 citations. Previous affiliations of Andrea Glasauer include Bayer HealthCare Pharmaceuticals.
Papers
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Journal ArticleDOI
Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis
William W. Wheaton,Samuel E. Weinberg,Robert B. Hamanaka,Saul Soberanes,Lucas B. Sullivan,Elena Anso,Andrea Glasauer,Eric Dufour,Gökhan M. Mutlu,GR Scott Budigner,Navdeep S. Chandel +10 more
TL;DR: In human cancer cells, metformin inhibits mitochondrial complex I (NADH dehydrogenase) activity and cellular respiration, indicating that cancer cells rely exclusively on glycolysis for survival in the presence of meetformin.
Journal ArticleDOI
Targeting antioxidants for cancer therapy.
TL;DR: This review discusses the controversial role of ROS in tumorigenesis and especially elaborate on the advantages of targeting ROS scavengers, hence the antioxidant capacity of cancer cells, and how this can be utilized for cancer therapeutics.
Journal ArticleDOI
Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development.
Robert B. Hamanaka,Andrea Glasauer,Paul Hoover,Shuangni Yang,Hanz Blatt,Andrew R. Mullen,Spiro Getsios,Cara J. Gottardi,Ralph J. DeBerardinis,Robert M. Lavker,Navdeep S. Chandel +10 more
TL;DR: Findings indicate that mitochondria-generated ROS are critical mediators of cellular differentiation and tissue morphogenesis.
Journal ArticleDOI
Targeting SOD1 reduces experimental non–small-cell lung cancer
TL;DR: It is found that ATN-224–induced cell death was mediated through H(2)O(2)-dependent activation of P38 MAPK and that P38 activation led to a decrease in the antiapoptotic factor MCL1, which is often upregulated in NSCLC.
Peer ReviewDOI
Author response: Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis
William W. Wheaton,Samuel E. Weinberg,Robert B. Hamanaka,Saul Soberanes,Lucas B. Sullivan,Elena Anso,Andrea Glasauer,Eric Dufour,Gökhan M. Mutlu,GR Scott Budigner,Navdeep S. Chandel +10 more