Andreas Beineke

TL;DR: DL represents a biphasic disease process consisting of an initial direct virus-mediated process and immune-mediated plaque progression, and an altered balance between matrix metalloproteinases and their inhibitors seems to play a pivotal role for the pathogenesis of DL.

TL;DR: Lethal infections have been described in non-carnivore species such as peccaries and non-human primates demonstrating the remarkable ability of the pathogen to cross species barriers.

TL;DR: A mouse model of staphylococcal hematogenous osteomyelitis precisely reproduces most features of the human disease, ideal for testing and monitoring novel treatment modalities via noninvasive imaging.

TL;DR: Interestingly, quantitative RT-PCR from different organs and tissues, together with the presence of an miR-122 binding site in the viral genome, strongly suggests a liver tropism for bovine hepacivirus, making this novel virus a promising animal model for HCV infections in humans.

TL;DR: The results indicate that expansion of MDSC and, to a minor degree, of regulatory T cells in S. aureus–infected mice may create an immunosuppressive environment that sustains chronic infection.