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Andrés Caicedo
Researcher at Universidad San Francisco de Quito
Publications - 48
Citations - 1226
Andrés Caicedo is an academic researcher from Universidad San Francisco de Quito. The author has contributed to research in topics: Medicine & Mitochondrion. The author has an hindex of 10, co-authored 29 publications receiving 696 citations. Previous affiliations of Andrés Caicedo include French Institute of Health and Medical Research & University of Montpellier.
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Journal ArticleDOI
Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment
Pedro M. Aponte,Andrés Caicedo +1 more
TL;DR: This review will explore properties shared between normal and malignant Stem Cells, including Mesenchymal Stem/Stromal Cells (MSCs), which, although their stemness properties are limited, represent essential components of the Stem Cell niche and tumor microenvironment.
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MitoCeption as a new tool to assess the effects of mesenchymal stem/stromal cell mitochondria on cancer cell metabolism and function
Andrés Caicedo,Vanessa Fritz,Jean-Marc Brondello,Mickaël Ayala,Indira Dennemont,Naoill Abdellaoui,Florence de Fraipont,Anaïck Moisan,Claire Angebault Prouteau,Hassan Boukhaddaoui,Christian Jorgensen,Marie-Luce Vignais +11 more
TL;DR: The transfer of minute amounts of mesenchymal stem/stromal cell (MSC) mitochondria to cancer cells, a process otherwise occurring naturally in coculture, results in cancer cell enhanced oxidative phosphorylation (OXPHOS) activity and favors cancer cell proliferation and invasion.
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Cell Connections by Tunneling Nanotubes: Effects of Mitochondrial Trafficking on Target Cell Metabolism, Homeostasis, and Response to Therapy.
TL;DR: MSCs are now the focus of intense scrutiny due to their capacity to form TNTs and transfer mitochondria to target cells, leading to changes in cell energy metabolism and functions, as described in this review.
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Artificial Mitochondria Transfer: Current Challenges, Advances, and Future Applications.
Andrés Caicedo,Pedro M. Aponte,Francisco Cabrera,Francisco Cabrera,Carmen Hidalgo,Maroun Khoury +5 more
TL;DR: The objective of this review is to outline existing artificial mitochondria transfer techniques and to describe the future steps necessary to develop new therapeutic applications in medicine, as mitochondria are more than mere cell power plants as they continue to discover their potential to be used in medicine.
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Forms of extracellular mitochondria and their impact in health
TL;DR: Evidence is provided of why extracellular mitochondria and their varying forms are considered regenerative factors or pro-inflammatory activators and the base of their use in therapy or as a biomarker of disease severity and prognosis.