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Andrew Ching
Researcher at ZymoGenetics
Publications - 8
Citations - 3719
Andrew Ching is an academic researcher from ZymoGenetics. The author has contributed to research in topics: Peptide sequence & Complementary DNA. The author has an hindex of 8, co-authored 8 publications receiving 3625 citations.
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Journal ArticleDOI
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
Julia Parrish-Novak,Stacey R. Dillon,Andrew Nelson,Angie Hammond,Cindy A. Sprecher,Jane A. Gross,Janet V. Johnston,Karen L. Madden,Wenfeng Xu,James A. West,Sara K. Schrader,Steve K. Burkhead,Mark D. Heipel,Cameron S. Brandt,Joseph L. Kuijper,Janet M. Kramer,Darrell C. Conklin,Scott R. Presnell,Jon Berry,Faith Shiota,Susan Bort,Kevin Hambly,Sherri Mudri,Chris Clegg,Margaret D. Moore,Francis J. Grant,Catherine Lofton-Day,Teresa Gilbert,Fenella C. Raymond,Andrew Ching,Lena Yao,Deborah L. Smith,Philippa J. Webster,Theodore E. Whitmore,Mark F. Maurer,Kenneth Kaushansky,Rick D. Holly,Don Foster +37 more
TL;DR: In vitro assays suggest that IL21 has a role in the proliferation and maturation of natural killer cell populations from bone marrow, in theiferation of mature B-cell populations co-stimulated with anti-CD40, and in the growth of T cells co- Stimulated withAnti-CD3.
Journal ArticleDOI
Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo
Si Lok,Kenneth Kaushansky,Richard D. Holly,Joseph L. Kuijper,Catherine Lofton-Day,Oort Pieter J,Francis J. Grant,Mark D. Heipel,Steve K. Burkhead,Janet M. Kramer,L. Anne Bell,Cindy A. Sprecher,Hal Blumberg,Rebecca A. Johnson,Donna E. Prunkard,Andrew Ching,Shannon Mathewes,Mason C. Bailey,John W. Forstrom,Michele M. Buddle,Sherri G. Osborn,Simon J. Evans,Paul O. Sheppard,Scott R. Presnell,Patrick J. O'Hara,Fredrick S. Hagen,Gerald Juergen Roth,Donald C. Foster +27 more
TL;DR: The functional cloning of a murine complementary DNA encoding a ligand for the receptor encoded by the c-mpl proto-oncogene is reported, and results strongly suggest that theligand for c-Mpl is thrombopoietin.
Journal ArticleDOI
Cloning and characterization of human protease-activated receptor 4
Wenfeng Xu,Henrik Andersen,Theodore E. Whitmore,Scott R. Presnell,David P. Yee,Andrew Ching,Teresa Gilbert,Earl W. Davie,Donald C. Foster +8 more
TL;DR: Northern blot showed that PAR4 mRNA was expressed in a number of human tissues, with high levels being present in lung, pancreas, thyroid, testis, and small intestine.
Journal ArticleDOI
Human thrombopoietin: gene structure, cDNA sequence, expression, and chromosomal localization.
D C Foster,Cindy A. Sprecher,Francis J. Grant,J M Kramer,Joseph L. Kuijper,R.D. Holly,Theodore E. Whitmore,M.D. Heipel,L. A. Bell,Andrew Ching +9 more
TL;DR: A cDNA encoding a ligand for the murine c-mpl protooncogene is isolated and shown to be TPO, a lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from committed progenitor cells.
Journal ArticleDOI
Identification of INSL5, a new member of the insulin superfamily.
Darrell C. Conklin,Catherine Lofton-Day,Betty A. Haldeman,Andrew Ching,Theodore E. Whitmore,Si Lok,Stephen R. Jaspers +6 more
TL;DR: A new member of the insulin gene superfamily (INSL5) was identified by searching EST databases for the presence of the conserved insulin B-chain cysteine motif by radiation hybrid mapping and the use of surrounding markers.