D
Don Foster
Researcher at ZymoGenetics
Publications - 27
Citations - 9028
Don Foster is an academic researcher from ZymoGenetics. The author has contributed to research in topics: Cytokine & Interleukin 21. The author has an hindex of 22, co-authored 27 publications receiving 8615 citations. Previous affiliations of Don Foster include University of Washington & Novo Nordisk.
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Journal ArticleDOI
IL-28, IL-29 and their class II cytokine receptor IL-28R.
Paul O. Sheppard,Wayne R. Kindsvogel,Wenfeng Xu,Katherine E. Henderson,Stacy Schlutsmeyer,Theodore E. Whitmore,Rolf E. Kuestner,Ursula Garrigues,Carl W. Birks,Jenny Roraback,Craig D. Ostrander,Dennis L. Dong,Jinu Shin,Scott R. Presnell,Brian A. Fox,Betty A. Haldeman,Emily Cooper,David W. Taft,Teresa Gilbert,Francis J. Grant,Tackett Monica L,William Krivan,Gary L. McKnight,Chris Clegg,Don Foster,Kevin M. Klucher +25 more
TL;DR: A family of three cytokines, designated interleukin 28A, IL-28B and IL-29, that are distantly related to type I interferons (IFNs) and the IL-10 family are identified and may serve as an alternative totype I IFNs in providing immunity to viral infection.
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TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
Jane A. Gross,Janet V. Johnston,Sherri Mudri,Rachel Enselman,Stacey R. Dillon,Karen L. Madden,Wenfeng Xu,Julia Parrish-Novak,Don Foster,Catherine Lofton-Day,Margaret D. Moore,Alisa Littau,Angelika Grossman,Harald S. Haugen,Kevin P. Foley,Hal Blumberg,Kim Harrison,Wayne R. Kindsvogel,Christopher H. Clegg +18 more
TL;DR: These findings demonstrate the involvement of zTNF4 and its receptors in the development of SLE and identify TACI–Ig as a promising treatment of autoimmune disease in humans.
Journal ArticleDOI
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
Julia Parrish-Novak,Stacey R. Dillon,Andrew Nelson,Angie Hammond,Cindy A. Sprecher,Jane A. Gross,Janet V. Johnston,Karen L. Madden,Wenfeng Xu,James A. West,Sara K. Schrader,Steve K. Burkhead,Mark D. Heipel,Cameron S. Brandt,Joseph L. Kuijper,Janet M. Kramer,Darrell C. Conklin,Scott R. Presnell,Jon Berry,Faith Shiota,Susan Bort,Kevin Hambly,Sherri Mudri,Chris Clegg,Margaret D. Moore,Francis J. Grant,Catherine Lofton-Day,Teresa Gilbert,Fenella C. Raymond,Andrew Ching,Lena Yao,Deborah L. Smith,Philippa J. Webster,Theodore E. Whitmore,Mark F. Maurer,Kenneth Kaushansky,Rick D. Holly,Don Foster +37 more
TL;DR: In vitro assays suggest that IL21 has a role in the proliferation and maturation of natural killer cell populations from bone marrow, in theiferation of mature B-cell populations co-stimulated with anti-CD40, and in the growth of T cells co- Stimulated withAnti-CD3.
Journal ArticleDOI
Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice.
Stacey R. Dillon,Cindy A. Sprecher,Angela K. Hammond,Janine Bilsborough,Maryland Rosenfeld-Franklin,Scott R. Presnell,Harald S. Haugen,Mark F. Maurer,Brandon Harder,Janet V. Johnston,Susan Bort,Sherri Mudri,Joseph L. Kuijper,Tom Bukowski,Pamela Shea,Dennis L. Dong,Maria M. Dasovich,Francis J. Grant,Luann Lockwood,Steven D. Levin,Cosette LeCiel,Kim Waggie,Heather Day,Stavros Topouzis,Janet M. Kramer,Rolf E. Kuestner,Zhi Chen,Don Foster,Julia Parrish-Novak,Jane A. Gross +29 more
TL;DR: Data indicate that IL-31 may be involved in promoting the dermatitis and epithelial responses that characterize allergic and non-allergic diseases.
Journal ArticleDOI
Interleukin 20: discovery, receptor identification, and role in epidermal function.
Hal Blumberg,Darrell C. Conklin,Wenfeng Xu,Angelika Grossmann,Ty Brender,Susan Carollo,Maribeth A. Eagan,Don Foster,Betty A. Haldeman,Angie Hammond,Harald S. Haugen,Laura J. Jelinek,James D. Kelly,Karen L. Madden,Mark F. Maurer,Julia Parrish-Novak,Donna E. Prunkard,Shannon L. Sexson,Cindy A. Sprecher,Kim Waggie,James W. West,Theodore E. Whitmore,Lena Yao,Melanie K. Kuechle,Beverly A. Dale,Yasmin A. Chandrasekher +25 more
TL;DR: A structural, profile-based algorithm was used to identify interleukin 20 (IL-20), a novel IL-10 homolog, and an IL-20 receptor was identified as a heterodimer of two orphan class II cytokine receptor subunits that are expressed in skin and are dramatically upregulated in psoriatic skin.