A
Andrew P. Levy
Researcher at Brigham and Women's Hospital
Publications - 7
Citations - 2237
Andrew P. Levy is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Vascular endothelial growth factor & Vascular endothelial growth factor A. The author has an hindex of 5, co-authored 7 publications receiving 2216 citations.
Papers
More filters
Journal ArticleDOI
Transcriptional Regulation of the Rat Vascular Endothelial Growth Factor Gene by Hypoxia
TL;DR: A 28-base pair element in the 5′ promoter that mediates hypoxia-inducible transcription in transient expression assays is identified and sequence motifs in the 3′-untranslated region that may mediate VEGF mRNA stability are revealed.
Journal ArticleDOI
Post-transcriptional Regulation of Vascular Endothelial Growth Factor by Hypoxia
TL;DR: A significant post-transcriptional component to the regulation of VEGF is demonstrated, which demonstrates a discrepancy between the transcription rate and the steady-state mRNA level induced by hypoxia.
Journal ArticleDOI
Regulation of Vascular Endothelial Growth Factor in Cardiac Myocytes
Andrew P. Levy,Nina S. Levy,Joseph Loscalzo,Angelino Calderone,N Takahashi,Kiang-Teck Yeo,Gideon Koren,Wilson S. Colucci,Mark A. Goldberg +8 more
TL;DR: In the present study, VPF/VEGF mRNA and protein were demonstrated to be markedly stimulated in primary rat cardiac myocytes in vitro in response to reduction of the oxygen tension to 1% or inhibition of the electron transport chain, suggesting that more than one signal transduction pathway is involved in regulating VPF-VEGF expression.
Journal ArticleDOI
Regulation of Vascular Endothelial Growth Factor Expression by Insulin-Like Growth Factor I
Rinaa S. Punglia,Ming Lu,Julia Hsu,Masatoshi Kuroki,Masatoshi Kuroki,Michael J. Tolentino,Michael J. Tolentino,Karen Keough,Andrew P. Levy,Nina S. Levy,Mark A. Goldberg,Robert J. D'Amato,Robert J. D'Amato,Anthony P. Adamis,Anthony P. Adamis +14 more
TL;DR: In this article, the authors showed that insulin-like growth factor I (IGF-I) and vascular endothelial growth factor (VEGF) levels are correlated with retinal ischemia-associated intraocular neovascularization in humans.
Patent
Induction of vascular endothelial growth factor (VEGF) by transition metals
Mark A. Goldberg,Andrew P. Levy +1 more
TL;DR: Transition metal ions enhance the ability of the body to increase vascularization, particularly for revascularizing damaged tissues, apparently because they enhance expression of the vegF gene, so as to increase VEGF levels as discussed by the authors.