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Andrew P. Waters
Researcher at University of Glasgow
Publications - 229
Citations - 19210
Andrew P. Waters is an academic researcher from University of Glasgow. The author has contributed to research in topics: Plasmodium berghei & Plasmodium falciparum. The author has an hindex of 70, co-authored 226 publications receiving 17816 citations. Previous affiliations of Andrew P. Waters include Loyola University Medical Center & Walter and Eliza Hall Institute of Medical Research.
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Journal ArticleDOI
Genomics and malaria control.
TL;DR: The genomic sequences of themalarial vector, parasite, and host — the three components of the malarial transmission system — have been known for at least two years and it may be possible to counter their effects.
Journal ArticleDOI
Comparison of introns in a cdc2-homologous gene within a number of Plasmodium species.
Rinke Vinkenoog,Barbera Veldhuisen,Márcia Aparecida Sperança,Hernando A. del Portillo,Chris J. Janse,Andrew P. Waters +5 more
TL;DR: Interspecific comparison of intron sequences agreed with the previously inferred evolutionary relationships of the malaria parasites, and no conservation at the level of secondary structure could be detected, even between highly similar introns.
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Genome wide analysis of inbred mouse lines identifies a locus containing Ppar-γ as contributing to enhanced malaria survival.
Selina Bopp,Vandana Ramachandran,Kerstin Henson,Kerstin Henson,Angelina Luzader,Merle Lindstrom,Muriel Spooner,Brian M. Steffy,Oscar Suzuki,Chris J. Janse,Andrew P. Waters,Yingyao Zhou,Tim Wiltshire,Elizabeth A. Winzeler,Elizabeth A. Winzeler +14 more
TL;DR: This work has used a mouse model to detect genes involved in the resistance or susceptibility to Plasmodium berghei malaria infection and found a locus on chromosome 6 that contains only two genes and confirms the importance of Ppar-γ in malaria infection.
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Has the time come for us to complement our malaria parasites
TL;DR: Genetic complementation of Plasmodium knockout mutants is highly desirable and should be attempted whenever possible, and southern analysis (PFG-separated chromosomes and/or restricted genomic DNA) should be considered to be the gold standard.