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Anette Fiebeler
Researcher at Hannover Medical School
Publications - 56
Citations - 4564
Anette Fiebeler is an academic researcher from Hannover Medical School. The author has contributed to research in topics: Angiotensin II & Renin–angiotensin system. The author has an hindex of 31, co-authored 56 publications receiving 4415 citations. Previous affiliations of Anette Fiebeler include Max Delbrück Center for Molecular Medicine & Charité.
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Journal ArticleDOI
NF-κB Inhibition Ameliorates Angiotensin II–Induced Inflammatory Damage in Rats
Dominik N. Müller,Ralf Dechend,Eero Mervaala,Joon-Keun Park,Folke Schmidt,Anette Fiebeler,Jürgen Theuer,Volker Breu,Detlev Ganten,Hermann Haller,Friedrich C. Luft +10 more
TL;DR: It is demonstrated that the antioxidant pyrrolidine dithiocarbamate inhibits NF-kappaB activity, ameliorates inflammation, and protects against angiotensin II-induced end-organ damage.
Journal ArticleDOI
AT1 Receptor Agonistic Antibodies From Preeclamptic Patients Stimulate NADPH Oxidase
Ralf Dechend,Christiane Viedt,Dominik N. Müller,Bernhard Ugele,Ralf P. Brandes,Gerd Wallukat,Joon-Keun Park,Jürgen Janke,Peter Barta,Jürgen Theuer,Anette Fiebeler,Volker Homuth,Rainer Dietz,Hermann Haller,Jörg Kreuzer,Friedrich C. Luft +15 more
TL;DR: NADPH oxidase is potentially an important source of ROS that may upregulate NF-&kgr;B in preeclampsia and is suggested to contribute to ROS production and inflammatory responses in preeClampsia.
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Immunosuppressive treatment protects against angiotensin II-induced renal damage.
Dominik N. Müller,Dominik N. Müller,Erdenechimeg Shagdarsuren,Joon-Keun Park,Ralf Dechend,Eero Mervaala,Franziska Hampich,Anette Fiebeler,Xinsheng Ju,Piet Finckenberg,Jürgen Theuer,Jürgen Theuer,Christiane Viedt,Joerg Kreuzer,Harald Heidecke,Hermann Haller,Martin Zenke,Friedrich C. Luft +17 more
TL;DR: It is suggested that immunosuppression prevents dendritic cell maturation and T-cell infiltration in a nonimmune model of Ang II-induced renal damage, which may initiate events leading to innate and acquired immune response.
Journal ArticleDOI
Aliskiren, a Human Renin Inhibitor, Ameliorates Cardiac and Renal Damage in Double-Transgenic Rats
Bernhard Pilz,Erdenechimeg Shagdarsuren,Maren Wellner,Anette Fiebeler,Ralf Dechend,Petra Gratze,Silke Meiners,David Louis Feldman,Randy L. Webb,Ingrid M. Garrelds,A.H. Jan Danser,Friedrich C. Luft,Dominik N. Müller +12 more
TL;DR: It is concluded that in dTGR, equieffective antihypertensive doses of Val or aliskiren attenuated end-organ damage and compares favorably to angiotensin receptor blockade in reversing organ damage.
Journal ArticleDOI
Prorenin and Renin-Induced Extracellular Signal-Regulated Kinase 1/2 Activation in Monocytes Is Not Blocked by Aliskiren or the Handle-Region Peptide
Sandra Feldt,Wendy W. Batenburg,Istvan Mazak,Ulrike Maschke,Maren Wellner,Heda Kvakan,Ralf Dechend,Anette Fiebeler,Céline Burcklé,Aurelie Contrepas,A.H. Jan Danser,Michael Bader,Geneviève Nguyen,Friedrich C. Luft,Dominik N. Müller +14 more
TL;DR: Prorenin and renin-induced ERK 1/2 activation are independent of angiotensin II, and there is no evidence that HRP affects renin or prorenin binding and signaling.