A
Angela Rösen-Wolff
Researcher at University of Würzburg
Publications - 2
Citations - 436
Angela Rösen-Wolff is an academic researcher from University of Würzburg. The author has contributed to research in topics: Downregulation and upregulation & Germline mutation. The author has an hindex of 1, co-authored 2 publications receiving 420 citations.
Papers
More filters
Journal ArticleDOI
The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis.
Sharon E. Straus,Elaine S. Jaffe,Jennifer M. Puck,Janet K. Dale,Keith B. Elkon,Angela Rösen-Wolff,Anke M J Peters,Michael C. Sneller,Claire W. Hallahan,Jin Wang,Roxanne Fischer,Christine M. Jackson,Albert Y. Lin,Caroline Bäumler,Elke Siegert,Alexander Marx,Akshay K. Vaishnaw,Tamara Grodzicky,Thomas A. Fleisher,Michael J. Lenardo +19 more
TL;DR: Investigation of 10 patients and their relatives with Fas mutations revealed that all had defective lymphocyte apoptosis and most had other features of ALPS, implicate a role for Fas-mediated apoptosis in preventing B-cell and T-cell lymphomas.
Journal ArticleDOI
Angiogenesis in Multiple Myeloma (MM): Angiogenic Switch or Reflexion of Plasma Cell Number? A Gene Expression Based Survey in Primary Myeloma Cells and the Bone Marrow Microenvironment.
Dirk Hose,John DeVos,Christiane Heiß,Jean-François Rossi,Angela Rösen-Wolff,Axel Benner,Karène Mahtouk,Michael Hundemer,Thierry Rème,Jens Hillengass,Katja Herde,Uta Mazitschek,Jérôme Moreaux,Sabine Wenisch,Véronique Pantesco,Anna Jauch,Eric Jourdan,Hartmut Goldschmidt,Bernard Klein,Thomas Möhler +19 more
TL;DR: Upregulation of HGF-expression, downregulation of TIMP2, SERPINF1, COLA18A1, PF4, THBS1, CXCL14 expression in MMC as well as down regulation of PLAU and upregulation of TNFα in the BMME seem to indicate an “angiogenic switch”.