Ângelo R. Antoniolli

TL;DR: Information is added about the beneficial effects of carvacrol on mechanical hypernociception and inflammation and that this monoterpene might be potentially interesting in the development of novel tools for management and/or treatment of painful conditions, including those related to inflammatory and prooxidant states.

TL;DR: This study analyzed the factors that can influence on antimicrobial activity of essential oils, in vitro, based on preview data from literature and concluded that a large attention should be given to some factors when working with essential oils.

TL;DR: The T. avellanedae inner bark aqueous extract presented antinociceptive and antiedematogenic activities at the used models, with a possible antinOCiceptive effect associated to the adenosine system.

TL;DR: The opioids, serotonergic and cannabinoid systems are suggested as the most promising targets for the natural products described, suggesting that these compounds are possible candidates for the treatment of chronic painful conditions, such as neuropathic pain.

TL;DR: In the current study, the analgesic and free radical scavenging properties of an aqueous extract from the husk fiber of Cocos nucifera L. (Palmae) were demonstrated by the use of in vivo and in vitro models.