M
Marcio L. Rodrigues
Researcher at Federal University of Rio de Janeiro
Publications - 204
Citations - 9710
Marcio L. Rodrigues is an academic researcher from Federal University of Rio de Janeiro. The author has contributed to research in topics: Cryptococcus neoformans & Cryptococcosis. The author has an hindex of 50, co-authored 204 publications receiving 8007 citations. Previous affiliations of Marcio L. Rodrigues include Stony Brook University & Oswaldo Cruz Foundation.
Papers
More filters
Journal ArticleDOI
Extracellular Vesicles Produced by Cryptococcus neoformans Contain Protein Components Associated with Virulence
Marcio L. Rodrigues,Ernesto S. Nakayasu,Débora L. Oliveira,Leonardo Nimrichter,Joshua D. Nosanchuk,Igor C. Almeida,Arturo Casadevall +6 more
TL;DR: An efficient and general mechanism of secretion of pathogenesis-related molecules in C. neoformans is revealed, suggesting that extracellular vesicles function as “virulence bags” that deliver a concentrated payload of fungal products to host effector cells and tissues.
Journal ArticleDOI
Vesicular Polysaccharide Export in Cryptococcus neoformans Is a Eukaryotic Solution to the Problem of Fungal Trans-Cell Wall Transport
Marcio L. Rodrigues,Leonardo Nimrichter,Débora L. Oliveira,Susana Frases,Kildare Miranda,Oscar Zaragoza,Mauricio A. Álvarez,Antonio Nakouzi,Marta Feldmesser,Arturo Casadevall +9 more
TL;DR: It is demonstrated that C. neoformans produces extracellular vesicles during in vitro growth and animal infection and implies a novel mechanism for the release of the major virulence factor of C. Neoformans whereby polysaccharide packaged in lipid vesicle crosses the cell wall and the capsule network to reach the Extracellular environment.
Book ChapterDOI
The capsule of the fungal pathogen Cryptococcus neoformans
Oscar Zaragoza,Marcio L. Rodrigues,Magdia De Jesus,Susana Frases,Ekaterina Dadachova,Arturo Casadevall +5 more
TL;DR: An update on the current knowledge of the C. neoformans capsule is provided, covering aspects related to its structure, synthesis and particularly, its role as a virulence factor.
Journal ArticleDOI
EVpedia: a community web portal for extracellular vesicles research
Dae-Kyum Kim,Jaewook Lee,Sae Rom Kim,Dong-Sic Choi,Yae Jin Yoon,Ji-Hyun Kim,Gyeongyun Go,Dinh Nhung,Kahye Hong,Su Chul Jang,Si-Hyun Kim,Kyong-Su Park,Oh Youn Kim,Hyun Taek Park,Ji-Hye Seo,Elena Aikawa,Monika Baj-Krzyworzeka,Bas W.M. van Balkom,Mattias Belting,Lionel Blanc,Vincent C. Bond,Antonella Bongiovanni,Francesc E. Borràs,Luc Buée,Edit I. Buzás,Lesley Cheng,Aled Clayton,Emanuele Cocucci,Charles S. Dela Cruz,Dominic M. Desiderio,Dolores Di Vizio,Karin M. Ekström,Juan M. Falcón-Pérez,Chris Gardiner,Bernd Giebel,David W. Greening,Julia Christina Gross,Dwijendra K. Gupta,An Hendrix,Andrew F. Hill,Michelle M. Hill,Esther N. M. Nolte-‘t Hoen,Do Won Hwang,Jameel M. Inal,Medicharla V. Jagannadham,Muthuvel Jayachandran,Young Koo Jee,Malene Rytter Jørgensen,Kwang Pyo Kim,Yoon Keun Kim,Thomas Kislinger,Cecilia Lässer,Dong Soo Lee,Hakmo Lee,Johannes P.T.M. van Leeuwen,Thomas Lener,Ming-Lin Liu,Ming-Lin Liu,Jan Lötvall,Antonio Marcilla,Suresh Mathivanan,Andreas Möller,Jess Morhayim,François Mullier,Irina Nazarenko,Rienk Nieuwland,Diana N. Nunes,Ken C Pang,Ken C Pang,Jaesung Park,Tushar Patel,Gabriella Pocsfalvi,Hernando A. del Portillo,Ulrich Putz,Marcel I. Ramirez,Marcio L. Rodrigues,Marcio L. Rodrigues,Tae-Young Roh,Felix Royo,Susmita Sahoo,Raymond M. Schiffelers,Shivani Sharma,Pia Siljander,Richard J. Simpson,Carolina Soekmadji,Philip D. Stahl,Allan Stensballe,Ewa Stępień,Hidetoshi Tahara,Arne Trummer,Hadi Valadi,Laura J Vella,Sun Nyunt Wai,Kenneth W. Witwer,María Yáñez-Mó,Hyewon Youn,Reinhard Zeidler,Yong Song Gho +97 more
TL;DR: An improved version of EVpedia, a public database for EVs research, is presented, which contains a database of publications and vesicular components, identification of orthologous vesicle components, bioinformatic tools and a personalized function.
Journal ArticleDOI
Vesicular transport in Histoplasma capsulatum: an effective mechanism for trans-cell wall transfer of proteins and lipids in ascomycetes
Priscila C. Albuquerque,Ernesto S. Nakayasu,Marcio L. Rodrigues,Susana Frases,Arturo Casadevall,Rosely Maria Zancopé-Oliveira,Igor C. Almeida,Joshua D. Nosanchuk +7 more
TL;DR: The results demonstrate that H. capsulatum can utilize a trans‐cell wall vesicular transport secretory mechanism to promote virulence and support the proposal that vesicle secretion is a general mechanism in fungi for the transport of macromolecules related to virulence.