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Angelo Vacca
Researcher at University of Bari
Publications - 559
Citations - 24779
Angelo Vacca is an academic researcher from University of Bari. The author has contributed to research in topics: Angiogenesis & Bone marrow. The author has an hindex of 78, co-authored 531 publications receiving 21928 citations. Previous affiliations of Angelo Vacca include University of Foggia & University of Brescia.
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Journal Article
Bone marrow angiogenesis and progression in multiple myeloma
Roberto Ria,Antonia Reale,Annunziata De Luisi,Arianna Ferrucci,Michele Moschetta,Angelo Vacca +5 more
TL;DR: Since angiogenesis proceeds in step with the enlargement of plasma cell tumours and the activity phase in MM, its measurement could be a useful prognostic marker in patients with plasma cell proliferative disorders.
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Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma.
Angelo Vacca,Domenico Ribatti,Marco Presta,M Minischetti,Monica Iurlaro,Roberto Ria,Adriana Albini,Federico Bussolino,Franco Dammacco +8 more
TL;DR: Findings indicate that the progression of plasma cell tumors is accompanied by an increase of bone marrow neovascularization, which is dependent, at least in part, by FGF-2 and MMP-2 production.
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Bone marrow angiogenesis and progression in multiple myeloma.
Angelo Vacca,Domenico Ribatti,Luisa Roncali,Girolamo Ranieri,Gabriella Serio,Franco Silvestris,Franco Dammacco +6 more
TL;DR: In this article, the extent of bone marrow angiogenesis, evaluated as microvessel area, and the proliferating (S-phase) fraction of marrow plasma cells was evaluated as labelling index (LI), in patients with multiple myeloma (MM) and in those with monoclonal gammopathies of undetermined significance (MGUS).
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Human Erythropoietin Induces a Pro-Angiogenic Phenotype in Cultured Endothelial Cells and Stimulates Neovascularization In Vivo
Domenico Ribatti,Marco Presta,Marco Presta,Angelo Vacca,Angelo Vacca,Roberto Ria,Roberto Ria,Roberta Giuliani,Roberta Giuliani,Patrizia Dell'Era,Patrizia Dell'Era,Beatrice Nico,Beatrice Nico,Luisa Roncali,Luisa Roncali,Franco Dammacco,Franco Dammacco +16 more
TL;DR: The ability of Epo to interact directly with endothelial cells and to elicit an angiogenic response in vitro and in vivo is demonstrated and thus acts as a bona fide directAngiogenic factor.
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MHC Class I Antigen Processing and Presenting Machinery: Organization, Function, and Defects in Tumor Cells
TL;DR: Findings support the idea that APM defects are immune escape mechanisms that disrupt the tumor cells' ability to be recognized and killed by tumor antigen-specific cytotoxic CD8(+) T cells.