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Anil M. Sinha
Researcher at RWTH Aachen University
Publications - 39
Citations - 2491
Anil M. Sinha is an academic researcher from RWTH Aachen University. The author has contributed to research in topics: Cardiac resynchronization therapy & Heart failure. The author has an hindex of 18, co-authored 39 publications receiving 2439 citations.
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Journal ArticleDOI
Acute effects of cardiac resynchronization therapy on functional mitral regurgitation in advanced systolic heart failure
Ole A. Breithardt,Anil M. Sinha,Ehud Schwammenthal,Nadim Bidaoui,Kai U. Markus,Andreas Franke,Christoph Stellbrink +6 more
TL;DR: Functional mitral regurgitation is reduced by CRT in patients with HF and LBBB and the hypothesis that an increase in TMP, mediated by a rise in LV+dP/dt(max) due to more coordinated LV contraction, may facilitate effective mitral valve closure is supported.
Journal ArticleDOI
Echocardiographic quantification of left ventricular asynchrony predicts an acute hemodynamic benefit of cardiac resynchronization therapy
Ole A. Breithardt,Christoph Stellbrink,Andrew P. Kramer,Anil M. Sinha,Andreas Franke,Rodney W. Salo,Bernhard Schiffgens,Etienne Huvelle,Angelo Auricchio +8 more
TL;DR: Echocardiographic quantification of LV asynchrony identifies patients likely to have improved systolic function with CRT, and improved synchrony is directly related to improved hemodynamic syStolic function in type 2 patients.
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Cardiac resynchronization therapy can reverse abnormal myocardial strain distribution in patients with heart failure and left bundle branch block.
Ole A. Breithardt,Christoph Stellbrink,Lieven Herbots,Piet Claus,Anil M. Sinha,Bart Bijnens,Peter Hanrath,George R. Sutherland +7 more
TL;DR: Left bundle branch block can lead to a significant redistribution of abnormal myocardial fiber strains and these abnormal changes in the extent and timing of septal-lateral strain relationships can be reversed by CRT.
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Cardiac resynchronization therapyhomogenizes myocardial glucosemetabolism and perfusion in dilatedcardiomyopathy and left bundle branch block
B. Nowak,Anil M. Sinha,Wolfgang M. Schaefer,Karl-Christian Koch,Hans-Juergen Kaiser,Peter Hanrath,Udalrich Buell,Christoph Stellbrink +7 more
TL;DR: This work investigated whether cardiac resynchronization therapy (CRT) affects myocardial glucose metabolism and perfusion in dilated cardiomyopathy and left bundle branch block and found no effect on these parameters.
Journal ArticleDOI
Cryptogenic Stroke and underlying Atrial Fibrillation (CRYSTAL AF): design and rationale.
Anil M. Sinha,Hans-Christoph Diener,Carlos A. Morillo,Tommaso Sanna,Richard A. Bernstein,Vincenzo Di Lazzaro,Rod S. Passman,Frank Beckers,Johannes Brachmann +8 more
TL;DR: The CRYSTAL AF trial is a randomized prospective study to evaluate a novel approach to long-term monitoring for AF detection in patients with cryptogenic stroke using an insertable cardiac monitor.