Anita Martinac

TL;DR: In vitro release studies of liposomes incorporated in the hydrogel proved their applicability as a novel vaginal delivery system with localized and sustained release of encapsulated acyclovir.

TL;DR: Tensile studies showed that both, EC/CM ratio and the type of spray-dried system influenced the bioadhesive properties of the micro spheres in a way that the microspheres with higher chitosan content were more bioad adhesive and microsphere prepared from suspensions were moreBioadhesive than those prepared from emulsions, regardless of the same polymeric composition.

TL;DR: The data demonstrate that pellets composed of oil to surfactant ratio of 1:4 (w/w) presented improvement in performance in permeation experiments, and resulted in different formulations with improved drug solubility and permeability characteristics.

TL;DR: It was shown that particle size, swelling ability and loratadine release from spray-dried microspheres were significantly affected by the polymeric composition and feed concentration in Spray-drying process.

TL;DR: The results indicated that the entrapment efficiency (EE), as well as carbamazepine release profile, depended on polymeric composition and drug– polymer ratios of the microspheres prepared, and the bestEntrapment efficiencies were obtained when chitosan of low‐molecular‐weight (CL) or HPMC were used for the microencapsulation.