1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview

1,3,4-Thiadiazole: Synthesis, Reactions, and Applications in Medicinal, Agricultural, and Materials Chemistry

The challenges of the modern society and the growing demand of high-technology sectors of industrial production bring about a new phase in the development of organic synthesis. A cutting edge of modern synthetic methods is introduction of functional groups and more complex structural units into organic molecules with unprecedented control over the course of chemical transformation. Analysis of the state-of-the-art achievements in selective organic synthesis indicates the appearance of a new trend — the synthesis of organic molecules, biologically active compounds, pharmaceutical substances and smart materials with absolute selectivity. Most advanced approaches to organic synthesis anticipated in the near future can be defined as 'atomic precision' in chemical reactions. The present review considers selective methods of organic synthesis suitable for transformation of complex functionalized molecules under mild conditions. Selected key trends in the modern organic synthesis are considered including the preparation of organofluorine compounds, catalytic cross-coupling and oxidative cross-coupling reactions, atom-economic addition reactions, methathesis processes, oxidation and reduction reactions, synthesis of heterocyclic compounds, design of new homogeneous and heterogeneous catalytic systems, application of photocatalysis, scaling up synthetic procedures to industrial level and development of new approaches to investigation of mechanisms of catalytic reactions. The bibliography includes 840 references.

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Development of new methods in modern selective organic synthesis: preparation of functionalized molecules with atomic precision

An asymmetric approach toward chiral multicyclic spirooxindoles from isothiocyanato oxindoles and unsaturated pyrazolones by a chiral tertiary amine thiourea catalyst.

FeCl3-catalyzed stereoselective construction of spirooxindole tetrahydroquinolines via tandem 1,5-hydride transfer/ring closure.

Nitrogen‐, and/or Sulfur-Containing Heterocyclic Rings Poulomi Majumdar,†,‡ Anita Pati,†,§ Manabendra Patra, Rajani Kanta Behera,† and Ajaya Kumar Behera*,† †Organic Synthesis Laboratory, School of Chemistry, Sambalpur University, Jyoti Vihar, Burla 768019, Orissa, India ‡State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, P.R. China School of Applied Sciences (Chemistry), KIIT University, Bhubaneswar 751024, India National Institute of Science & Technology, Palur Hill, Berhampur 761068, Orissa, India

Acid hydrazides, potent reagents for synthesis of oxygen-, nitrogen-, and/or sulfur-containing heterocyclic rings.

Studies on Spiroheterocycles, Part II: Heterocyclization of the Spiro Compounds Containing Cyclohexanone and Thiobarbituric Acid with Different Bidentate Nucleophilic Reagents

Imidazole derivatives as the organic precursor of ZnO nano particle

Acid Hydrazides, Potent Reagents for Synthesis of Oxygen-, Nitrogen-, and/or Sulfur-Containing Heterocyclic Rings

A series of silver(I)-based coordination polymers (AgCPs) have been synthesized using three new nonchelating cis-bis-nitrile derivatives of oxa-bowls, L1–L3, as ligand components. The ligands are designed to provide conformational restrictions as well as semi-rigid directionality to the coordination vectors extended from the nitrile functionalities. The steric bulks around the oxa-bowl spacer moieties are gradually escalated to study their influence on the topologies of the ensuing AgCPs. Two silver salts i.e. AgSbF6 and AgPF6 are used to check the influence of anions on the structural architectures. Ziz-zag-sheet type 2-D AgCPs are formed with the ligands L1 and L2 possessing less steric bulk. All the metal centres are found to be tetracoordinated by nitrile-nitrogens of the same sheet giving distorted-bisphenoidal geometries. Additional short interactions of the silver(I) centres of a given sheet with the oxygen of the oxa-bowls belonging to the neighbouring stacked sheets are observed. The bulky ligand L3 behaved differently where the metal centres are tetracoordinated although only two of the ligating units are derived from the nitrile nitrogens and the remaining two are from, depending upon the counter anion, the counter anion/oxygen of oxa-bowls or two water molecules. The overall arrangements in the AgCPs of L3 are of the 2-D carpet type (for SbF6− ion) composed of interconnected chains, and 1-D ladder type (for PF6− ion) constructed from two chains. Cation–π interactions are found between the aromatic part of L3 of a given chain and the silver(I) of the adjacent chain that are interdigitated.

https://www.rsc.org/suppdata/ce/c3/c3ce41003j/c3ce41003j.pdf

Anita Pati

Papers

Acid hydrazides, potent reagents for synthesis of oxygen-, nitrogen-, and/or sulfur-containing heterocyclic rings.

Studies on Spiroheterocycles, Part II: Heterocyclization of the Spiro Compounds Containing Cyclohexanone and Thiobarbituric Acid with Different Bidentate Nucleophilic Reagents

Imidazole derivatives as the organic precursor of ZnO nano particle

Acid Hydrazides, Potent Reagents for Synthesis of Oxygen-, Nitrogen-, and/or Sulfur-Containing Heterocyclic Rings

Coordination polymers via self-assembly of silver(I) and cis-bis-nitrile-oxa-bowl derivatives