A
Ann-Mari Svennerholm
Researcher at University of Gothenburg
Publications - 270
Citations - 17594
Ann-Mari Svennerholm is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Enterotoxigenic Escherichia coli & Cholera. The author has an hindex of 73, co-authored 270 publications receiving 16892 citations. Previous affiliations of Ann-Mari Svennerholm include Johns Hopkins University & International Centre for Diarrhoeal Disease Research, Bangladesh.
Papers
More filters
Journal ArticleDOI
Enterotoxigenic escherichia coli in developing countries: epidemiology, microbiology, clinical features, treatment, and prevention
TL;DR: The pathogenesis of ETEC-induced diarrhea is similar to that of cholera and includes the production of enterotoxins and colonization factors, and clinical symptoms can range from mild diarrhea to a severe choline-like syndrome.
Journal ArticleDOI
Field trial of oral cholera vaccines in Bangladesh: results from three-year follow-up
John D. Clemens,David A. Sack,Jeffrey R. Harris,F. P. L. Van Loon,Jyotsnamoy Chakraborty,Firoz Ahmed,M. R. Rao,M. R. Khan,Yunus,Nurul Huda,Bonita F. Stanton,Bradford A. Kay,R Eeckels,Stephen D. Walter,Ann-Mari Svennerholm,Jan Holmgren +15 more
TL;DR: Protection was similar against severe and non-severe cholera, but was significantly lower in children who were vaccinated at 2-5 years than in older persons (63% for BS-WC; 68% for WC); and PE was substantially higher against classical cholero than against El Tor cholERA.
Journal ArticleDOI
Colonization factors of human enterotoxigenic Escherichia coli (ETEC)
Wim Gaastra,Ann-Mari Svennerholm +1 more
TL;DR: Enterotoxigenic Escherichia coli is the most common cause of childhood and travellers' diarrhoea and adhesion to the intestinal epithelium of the host is mediated by proteinaceous surface appendages called colonization factors.
Journal ArticleDOI
Identification ofEscherichia coli heat-labile enterotoxin by means of a ganglioside immunosorbent assay (GM1-ELISA) procedure
TL;DR: Enterotoxin titers determined with this GM1 enzyme-linked immunosorbent assay (ELISA) method agreed closely with those obtained with the adrenal cell bioassay, and should make it well suited for routine laboratory diagnosis of LT enterotoxigenicE.
Journal ArticleDOI
Cross-Protection by B Subunit-Whole Cell Cholera Vaccine Against Diarrhea Associated with Heat-Labile Toxin-Producing Enterotoxigenic Escherichia coli: Results of a Large-Scale Field Trial
John D. Clemens,David A. Sack,Jeffrey R. Harris,Jyotsnamoy Chakraborty,P. K. Neogy,Bonita F. Stanton,Nurul Huda,M. U. Khan,Bradford A. Kay,M. R. Khan,Mohammad Ansaruzzaman,M. Yunus,M. Raghava Rao,Ann-Mari Svennerholm,Jan Holmgren +14 more
TL;DR: Sixty-seven percent fewer episodes of LT-ETEC diarrhea were noted in the BS-WC group than in the WC group during short-term follow-up, but no reduction was evident during the ensuing nine months.