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Ann Michelle Stanley Morrison
Researcher at Woods Hole Oceanographic Institution
Publications - 2
Citations - 113
Ann Michelle Stanley Morrison is an academic researcher from Woods Hole Oceanographic Institution. The author has contributed to research in topics: Strongylocentrotus purpuratus & Functional divergence. The author has an hindex of 2, co-authored 2 publications receiving 103 citations.
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Cytochrome P450 1 Genes in Early Deuterostomes (Tunicates and Sea Urchins) and Vertebrates (Chicken and Frog): Origin and Diversification of the CYP1 Gene Family
Jared V. Goldstone,Heather M. H. Goldstone,Ann Michelle Stanley Morrison,Ann M. Tarrant,Suzanne E. Kern,Bruce R. Woodin,John J. Stegeman +6 more
TL;DR: Canonical xenobiotic response elements are present in the upstream genomic sequences of most tunicate and sea urchin CYP1s, and both groups are predicted to possess an aryl hydrocarbon receptor (AHR), suggesting possible regulatory linkage of AHR and these CYPs.
Journal ArticleDOI
Identification, modeling and ligand affinity of early deuterostome CYP51s, and functional characterization of recombinant zebrafish sterol 14α-demethylase
Ann Michelle Stanley Morrison,Jared V. Goldstone,David C. Lamb,Akira Kubota,Benjamin Lemaire,John J. Stegeman +5 more
TL;DR: Biochemical and computational analyses are consistent with lanosterol being a substrate for early deuterostome CYP51s, and the results expand the phylogenetic view of animal CYP 51, with evolutionary, environmental and therapeutic implications.